A cultural ecological perspective is valuable in identifying the complex relationship among ecology, culture, society, economy, demography and preference of particular gender especially male preferences. An evolutionary psychology explanation of female infanticide should take into account the role of cultural practices and ecological pressures in shaping psychological antecedents to treating differently even for own genes i.e. male preference and female neglect. In this regards, the relationship between ecology and culture is dynamic, and that macro interventions, such as building of cities, urbanization, development of highways, constructions of high dams in a physical development and advancement of socio-economic parameters associated with human development including leadership development, sustainability, sustainable use of resources, maintain equilibrium among population and resources and opportunities including empowerment of women, ultimately resulting in tightening the screw of social control of women’s sexuality. There should be maintained delicate balance between the relationship between women-men, women-women, and men-men, economically, demographically, socially, physically ecologically biologically or say culturally symbiotic in various forms as a husband or a son or a brother. From the study, it is concluded that, though society and culture are modern, heterogeneous, complex, advancing the conservative or traditional practices of son preference or discrimination based on gender are still practiced and are prevalent in our society and continue to define gender roles and practices especially among the middle-classes that found in Kathmandu. Therefore, son preference, for the middle-class women in Kathmandu, should not be understood superficially. It is a complex whole and it should be studied critically in detail.
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