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ABB is an international journal dedicated to the latest advancements in biosciences. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of biosciences. All manuscripts must be prepare…
Julia Howard
There is increasing evidence for the cytokine hypothesis, which states that exposure to elevated cytokines in utero due to maternal immune activation is a major risk factor for the development of schizophrenia later in life. This is supported by numerous epid…
Hui Tang, Umme Amara, Dora Tang, Mark A. Barnes, Christine McDonald, Laura E. Nagy
The innate immune response is a complex process involving multiple pathogen-recognition receptors, including toll-like receptors (TLRs) and nucleotide-binding oligomerization domain (NOD)-like receptors. Complement is also a critical component of innate immun…
Yun-Jung Lee, Young-Hye Moon, Kyeong Eun Hyung, Jong-Sun Yoo, Mi Ji Lee, Ik Hee Lee, Byung Sung Go, Kwang Woo Hwang
Activated macrophages have been simply de?ned as cells that secrete in?ammatory mediators and kill intracellular pathogens until few years ago. Recent studies have proposed a new classification system to separate activated macrophages based on their functiona…
Alessandra Spano, Sergio Barni, Vittorio Bertone, Luigi Sciola
In this work, the influence of different substrate ad hesion during phorbol-12-myristate-13-acetate (PMA)-induced differentiation of THP-1 monocytic cell line was studied. In particular, by morphocytochemical and cytometric approaches, the influence of type I…
Yuriko Hirono, Yasuyuki Tanahashi, Kazuma Sasaki, Kenjiro Konno, Yuki Shirai, Kengo Kobayashi, Azusa Someya, Sumire Inaga, Masaaki Sakura, Kent E. Pinkerton, Minoru Takeuchi
Alveolar macrophages (AM) are known to play an essential role in lung defense through their ability to remove the foreign matters reaching the lung alveoli. Cigarette smoke (CS) is a critical risk factor for many lung diseases. CS is inhaled into the lung by…
Shu-Chih Chen, Stephen A. Vitkun, Steven C. Quay
Background: The ability to identify asymptomatic women at high risk for breast cancer using known pre-malignant changes in exfoliative cytopathology of nipple aspirate fluid is of clinical importance. Exfoliative cytopathology of Nipple Aspirate Fluid (NAF) h…
Khrystyna Strus, Antonina Yashchenko, Olena Smolkova, Olga Nakonechna
Amount of thyroid pathology patients in Ukraine increased 3.7 times from 0.9 to 3.5 per 1000 population within a decade. The main reason of most of organs damage associated with hypothyroidism is decreased synthesis of number of cellular enzymes because of th…
Ebtesam M. Abd-El-Basse
Reactive astrogliosis has been implicated in the failure of axonal regeneration in adult mammalian Central Nervous System (CNS). It is our hypothesis that inflammatory cytokines act upon astrocytes to alter their biochemical and physical properties, which may…
Maria Pia Paroli, Alessandro Abbouda, Irene Abicca, Alfredo Sapìa, Marino Paroli
Inflammatory uveitis is a difficult condition to treat. Recently, a new class of drugs obtained by a biological process and therefore defined as “biologics” has been successfully used in the treatment of immunemediated rheumatic diseases. These drugs target d…
Charles I. Ezeamuzie, Hanan Zamil, Hawraa Al-Baghli, Ivan O. Edafiogho
CEE-1 (ethyl 4-phenylhydrazinocyclohex-3-en-2-oxo-6-phenyl-1-oate) — a novel enhydrazone ester, was tested in vitro for anti-inflammatory activity against the release of pro-inflammatory cytokine and prostanoid from lipopolysaccharide-activated human monocyte…
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ABB is an international journal dedicated to the latest advancements in biosciences. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of biosciences. All manuscripts must be prepare… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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