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ABB is an international journal dedicated to the latest advancements in biosciences. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of biosciences. All manuscripts must be prepare…
Baljinder Singh, Jagdeep Kaur, Kashmir Singh
Degradation of a pesticide, malathion, in soil by Bacillus sp has been reported during current study. A simple and highly sensitive reverse phase HPLC-UV (High pressure liquid chromatography-Ultraviolet) method was used for determination of malathion de grada…
Pamela Fernandez, Jessica Moreno, Claudio Barrientos, Sergio A. Aguila, Daniela Leon, Sebastián Ortiz, Ramon Silva, Francisco Rodriguez, Maritza Leonardi, Violeta Morin, Ximena Romo
Ethanol (EtOH) enhances glycinergic currents in the central nervous system (CNS). Because evidence for an interaction between the α 1 subunit of the glycine receptor ( α 1GlyR) and the G protein G βγ subunit exists in vitro and because cAMP levels are known t…
Anke Kopacek, Thomas Böldicke, Sarah Lergenmüller, Frank Berthold, Markus Jensen, Peter P. Müller, Ludger Grosse-Hovest
Bispecific antibodies are recombinant proteins with novel immunological properties and therapeutic potential. Recombinant protein quality and activity of several bispecific antibodies comprising different va riable domain combinations with respect to the pare…
Puspasree Puhan, Ebrahimali Abubacker Siddiq
Understanding the control of related molecular mechanisms is impossible without efficient and reproducible regeneration and stable genetic transformation. The key factors for enhancing successful regeneration are genotypes, tissue source of explants, combinat…
Tatsuro Shibui, Keisuke Bando, Satoru Misawa
DNA fragments encoding the light chain and heavy chain genes of an anti-human HER II antibody, trastuzumab, fused with an egg-lysozyme signal peptide were synthesized based on the codon bias of the methylotrophic yeast Pichia pastoris . These fragments were i…
José Pérez, Caridad Díaz, Irene G. Salado, Daniel I. Pérez, Fernando Peláez, Olga Genilloud, Francisca Vicente
It is a common practice in drug discovery organizations to screen new chemical entities in order to predict future drug-drug interactions. For this purpose, there are two main assay strategies, one based on recombinant cytochrome P450 (rCYP) enzymes and fluor…
Constance Vennin, Fatima Dahmani, Nathalie Spruyt, Eric Adriaenssens
In the past decade, studies of non-coding RNAs increase. Non-coding RNAs are divided in two classes: small and long non-coding RNA. It was shown that long non-coding RNAs regulate expression of 70% of genes. Long non-coding RNAs are involved in several cellul…
Sayak Ganguli, Sasti Gopal Das, Hirak Jyoti Chakraborty, Sohini Gupta, Abhijit Datta
MicroRNAs have emerged as one of the major classes of non-coding RNAs. Recent reports have placed them in high abundance in the nervous system, having key roles in development. Neurological disorders such as Parkinson’s disease, Alzheimer’s disease as well as…
Maria Rosa Garcia-Silva, Florencia Cabrera-Cabrera, Maria Catalina Güida, Alfonso Cayota
The complete understanding of the growing catalog of regulatory non-coding RNAs is going to shed light in different aspects of a wide range of pathogenic mechanisms in human diseases. This review was aimed to highlight recent advances in the small non- coding…
Harold S. Bernhardt, Warren P. Tate
Dimers of tRNAs can form through quasi self-complementary anticodon-anticodon interactions, for example at neutral pH in yeast tRNA Asp(GUC) and at pH4.5 in Escherichia coli tRNA Gly(GCC) through a partially protonated interaction. The requirements for tRNA o…
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ABB is an international journal dedicated to the latest advancements in biosciences. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of biosciences. All manuscripts must be prepare… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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