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ABB is an international journal dedicated to the latest advancements in biosciences. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of biosciences. All manuscripts must be prepare…
Udo Riss
Based on the theory of long distance interaction between antibodies and antigens we developed a theory of affinity maturation of antibodies that is based on longitudinale electric waves. Early stage antibodies show a wide frequency spectrum for antigens and a…
Takenori Shimizu, Kazuaki Yoshimune, Tomoe Komoriya, Takahiro Akiyama, Xujun Ye, Hideki Kohno
Aggregate amyloid beta protein 1-42 (A β 1-42 ) can typically be found in the early stage of Alzheimer’s disease (AD). A β 1-42 self-assembles and is highly toxic to neurons. Thus, recognizing aggregated A β 1-42 is very important for elucidation of A β 1-42…
Rajib Deb, Sandip Chakraborty, Belamaranahlly Veeregowda, Amit Kumar Verma, Ruchi Tiwari, Kuldeep Dhama
Since the discovery of hybridoma cells by Kohler and Milstein, the uses of monoclonal antibody (mAb), the protein produced by such cells are in vogue. Such antibodies with single isotype have higher specificity, and the serological tests employed in show high…
Baoling Lai, Chenhong Wang, Lu Zhou, Jie Wang, Huifen Wu
O bjective: To investigate the expression of catechol-O- methyltransferase (COMT) in placentas from term preeclampsia patients in a Chinese cohort and to analyze the relationships between COMT and mean artery pressure (MAP), serum uric acid and 24-hour urine…
Alexander Mader, Veronika Chromikova, Renate Kunert
For many years, the potential of immunoglobulin M (IgM) antibodies was not fully understood because of characteristics different to the well-known immunoglobulin G type like low target affinity, cross reactivity and complex protein structure. In the meanwhile…
Britta Hardy, Annat Raiter
The better understanding of the mechanism in which the immune system responds to the developing cancer provided the outcome in a new era in cancer immunotherapy. The tumor suppressive effect on the immune system is caused by negative T cell receptor signaling…
Carlos Rosales, Eileen Uribe-Querol
At the onset of an infection early defense systems, such as complement, get into action. Specialized leukocytes (white blood cells) of the innate immune sys tem, including monocytes, macrophages, and neutro phils also participate as a first line of defense ag…
Hang Fai Kwok
Cathepsin S is a cysteine protease highly expressed in many type of cancers including colorectal, prostate, breast, and glioblastoma’s. It is involved in tumor progression through extracellular matrix remodeling. In recent years, antibody research specificall…
Vera Codices, Olga Matos, Carlos Novo
With the discovery that the coccidian parasite Cryptosporidium sp. can cause severe symptoms in humans, many diagnostic techniques were quickly imple mented such as microscopic visualization, immunofluores cence and PCR. Currently, there is no effective drug…
Ellen Dirkx, Freek G. Bouwman, Didier Vertommen, Edwin C. Mariman, Sakthivel Sadayappan, Jan F. C. Glatz, Joost J. F. P. Luiken, Guillaume J. van Eys
Protein phosphorylation plays an important role in physiological processes, such as muscle contraction. Phospho-specific antibodies have become powerful tools to study these processes. Cardiac myosin binding protein-C (cMyBP-C) is one of the proteins that mak…
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ABB is an international journal dedicated to the latest advancements in biosciences. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of biosciences. All manuscripts must be prepare… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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