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ABB is an international journal dedicated to the latest advancements in biosciences. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of biosciences. All manuscripts must be prepare…
Koichiro Shiokawa
To study gene control mechanisms in Xenopus embryos, we analyzed polyamines, cloned SAMDC (S-adenosylmethionine decarboxylase), a key enzyme of polyamine metabolism, and microinjected its mRNA into Xenopus fertilized eggs. The microinjection induced a large i…
Sameer K. Muchhala, Kenza E. Benzeroual
Several studies have reported a relation between increased pro-inflammatory mediators such as TNF-α and apoptosis in neurodegenerative diseases such as Alzheimer’s disease (AD). It is known that lipopoly-saccharide (LPS) treatment induces neuroinflammation an…
Ravi Thakur, Durga Prasad Mishra
Cancer stem cells (CSCs) are tumor initiating cells within the tumor mass; that play a critical role in cancer pathogenesis. CSCs regulate cancer cell survival, metastatic potential, resistance to conventional radio-chemotherapy, disease relapse and poor prog…
Tie-Lou Chen, Er-Li Xu, Hui-Jie Lu, Heng Xu, Shi-Feng Wang, Hai-Jun Zhao, Yu-Ming Liu
Aim: Diabetes mellitus is a metabolic disorder leading to hyperglycemia and exhibiting altered fat and protein metabolism. Diabetes altered cellular microenvironment caused myriad untoward effects. Periodontitis is chronic inflammatory disease. Diabetes and p…
Bin Lu, Hong-Duo Chen, Hong-Guang Hong-Guang
Apoptosis is involved in aging and age-related disease, with respect to aging, apoptosis acting in a celltype-specific manner. The rate of apoptosis is elevated in-most types of aging cell populations and organs. In stable cells and certain continuously divid…
Bih-Rong Wei, Chuan Xu, Neal S. Rote
Transition from mononuclear villous cytotrophoblast into multinuclear syncytiotrophoblast in the human placenta is accompanied by changes in apoptosis-related proteins and an apparent increased resistance to induced apoptosis. We investigated the specific nat…
Guadalupe Soto-Rodríguez, Daniel Martínez-Fong, Rosa Arroyo, Patricia Aguilar-Alonso, Hector Rubio, José Ramón Eguibar, Araceli Ugarte, Maricela Torres-Soto, Juan Antonio González-Barrios, Jorge Cebada, Eduardo Brambila, Bertha Alicia Leon-Chavez
We previously showed that the increase in nitric oxide (NO) levels and NO synthase (NOS) expression correlate with the progression of reactive astrocytosis and demyelination in the brains of 6-month-old taiep rats. Increased levels of NO can result in high co…
Cynthia Patricia Nicholas, Sai-Peng Sim
Treatment with etoposide (VP-16) has been associated with translocation of the mixed lineage leukaemia ( MLL ) gene seen in treatment-related acute myeloid leukaemia (t-AML). Among the different partner genes, AF 9 is the most common partner gene of MLL. AF9…
Gregory Lee, Bixia Ge
Inhibitions or blockages of ligand-receptor interactions on cancer cell surfaces by exogenous competetors or antibodies often result in apoptosis or “programmed cell death.” The underlying mechanisms of action for cellular apoptosis depend greatly on the mole…
Jean-Marie Exbrayat, Elara N. Moudilou, Lucie Abrouk, Claire Brun
Amphibians and more particularly X. laevis are models often used for studying apoptosis during embryonic development. Using several methods, searchers determined the localization of programmed cell deaths (PCD). Several experimental methods also have been use…
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ABB is an international journal dedicated to the latest advancements in biosciences. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas of biosciences. All manuscripts must be prepare… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
Authors submit their manuscript, metadata, and declarations through the portal. There is no submission fee.
The editorial office screens the manuscript for scope, completeness, and formatting before assigning a handling editor.
At least two independent reviewers evaluate the manuscript under single-blind review. Where revisions are required, authors respond point by point.
On acceptance the article processing charge is invoiced and the CC BY 4.0 copyright handover is signed.
The article is copyedited, typeset, and given a DOI, then publishes open access with a permanent link.
Manuscripts must be original and not under consideration elsewhere. Submit in Microsoft Word or LaTeX with figures at 300 dpi minimum. Structure research articles as Abstract, Introduction, Methods, Results, Discussion, and References.
Use the journal's numbered (Vancouver) reference style. Cite sources consecutively in the order they appear, and ensure every reference is complete and retrievable.
Declare all funding sources, conflicts of interest, and ethical approvals (including informed consent and animal-care statements where applicable).