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Phage Display Technology, Phage Display System, Antibody Library, Prospects and Challenges
College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China
College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China
- 1 College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China
- 2 College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China
Advances in Microbiology·Volume 11 (2021)·Pages 181–189·Published 5 March 2021·DOI10.4236/aim.2021.113013
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Abstract
Phage display technology is a unique gene recombination expression technology, and it is also a simple and effective screening tool. Through panning, a protein or peptide with high affinity and selectivity to the target is obtained. Antibody phage display has become the first and most widely used in vitro screening technology. Phage display derivatives play an important role in the diagnosis and treatment of diseases. This article reviews the phage display system of phage display technology, the size and classification of antibody libraries and their applications, and discusses the application prospects and challenges of phage display technology. This thesis lays the foundation for the theoretical and experimental research of bacteriophages.
KeywordsResearch Progress of Phage Display System
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