Microbial Analysis of Urine and Antibiotic Sensitivity Pattern of Isolated Infectious Agents from Patients Suffering in Urinary Tract Infection
- 1 Department of Microbiology, Primeasia University, Dhaka, Bangladesh
- 2 Department of Infection Control, Lab Aid Hospital, Dhaka, Bangladesh
- 3 3M Healthcare and Food Safety Department, Globex Marketing Company Limited, Dhaka, Bangladesh
Abstract
This retrospective study was conducted at the National Institute of Neuroscience & Hospital, Agargaon, Dhaka from October, 2016 to March, 2017 with a view to finding out the incidence of UTI patients with aiming of testing & drug susceptibility. In order to conduct this study, consecutive urine samples of 200 of a total population of both sexes and various age groups were taken from both outpatient and inpatient departments. There were marked gender variations in all age groups, which comprised members between 2 and 80 years of age, and they were requested to provide urine samples for examination. Among them 22.50% of specimens yielded positive culture. UTI is more prevalent in females than in males. The most common isolates were E. coli (15%), Enterococcus sspp . (0.5%), Staphylococcus aureus (2.50%), Staphylococcus saprophyticus (3.50%) and pseudomanas (1.00%) . Azithromycin and ceftriaxone showed the highest sensitivity against E. coli but Nitrofuranton, Gentamicin and Cefixime showed comparatively lower sensitivity against E. coli . Nitrofuranton, and Cefurixime showed the highest sensitivity against S. saprophyticus but Ceftazidime showed the lowest sensitivity against S. saprophyticus. Meropenem showed the highest sensitivity against S. aureus but Ceftriaxone, Ceftazidime, Cefurixime, Amoxyxillin, Gentamicin and Nitrofuranton showed comparatively lower sensitivity against S. aureus . Azithromycin, Ciprofloxacin, Imupenem, Doxycyclin, Co-trimoxazole and Meropenem showed the highest sensitivity against Pseudomonas spp . but Nitrofuranton, Gentamicin, Amoxycillin, Cefurixime, Ceftazidime and Ceftriaxone showed comparatively lower sensitivity against Pseudomonas spp . All the antibiotics used showed 100% sensitivity against E nterococcus spp .
- Akortha, E.E. and Ibadin, O.K. (2008) Incidence and Antibiotic Susceptibility Pattern of Staphylococcus Aureus amongst Patients with Urinary Tract Infection (UTI) in UBTH Benin City, Nigeria. African Journal of Biotechnology , 7, 1637-1640. https://doi.org/10.5897/ajb08.176
- Foxman, B., Barlow, R., D’Arcy, H., Gillespie, B. and Sobel, J.D. (2000) Urinary Tract Infection. Annals of Epidemiology , 10, 509-515. https://doi.org/10.1016/s1047-2797(00)00072-7
- Adeleke, S. and Asani, M. (2009) Urinary Tract Infection in Children with Nephrotic Syndrome in Kano, Nigeria. Annals of African Medicine , 8, 38-41. https://doi.org/10.4103/1596-3519.55762
- Biyikli, N., Emre, S., Sirin, A. and Bilge, I. (2004) Biochemical Bone Markers in Nephrotic Children. Pediatric Nephrology , 19, 869-873. https://doi.org/10.1007/s00467-004-1537-6
- Ehinmidu, J.O. (2005) Antibiotics Susceptibility Patterns of Urine Bacterial Isolates in Zaria, Nigeria. Tropical Journal of Pharmaceutical Research , 2, 223-228. https://doi.org/10.4314/tjpr.v2i2.14603
- Hossain, G., Hossain, E., Ahammed, F., Kabir, M.R., Karmaker, G., Chowdhury, I.A., et al . (2020) Bacteriological Profile and Sensitivity Pattern of Urinary Tract Infection Patients in North East Part of Bangladesh. International Journal of Advances in Medicine , 7, 1614-1618. https://doi.org/10.18203/2349-3933.ijam20204510
- Foxman, B. (2003) Epidemiology of Urinary Tract Infections: Incidence, Morbidity, and Economic Costs. Disease - a - Month , 49, 53-70. https://doi.org/10.1016/s0011-5029(03)90000-9
- Abedin, M.Z., Faruque, M.O., Sifat, U.Z., Zaman, M., et al . (2020) Prevalence and in Vitro Antibiogram Patterns of Urinary Tract Pathogens in Rural Hospitals in Bangladesh. Journal of Chemical , Biological and Physical Sciences Section B , 10, 401-409.