Trends in Antimicrobial Resistance among Enterobacteriaceae Uropathogenic Strains in Burkina Faso: Insights from Six Years of Laboratory Data — Oak Academic Publishing
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Trends in Antimicrobial Resistance among Enterobacteriaceae Uropathogenic Strains in Burkina Faso: Insights from Six Years of Laboratory Data
Département de Biochimie-Microbiologie, Université Joseph KI-ZERBO, Ouagadougou, Burkina Faso
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Département de productions végétales, Centre Universitaire de Ziniaré, Ziniaré, Burkina Faso
,
Département de Biochimie-Microbiologie, Université Joseph KI-ZERBO, Ouagadougou, Burkina Faso
,
Département de Biochimie-Microbiologie, Université Joseph KI-ZERBO, Ouagadougou, Burkina Faso
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Département de la Biologie Médicale et de la Surveillance de la Maladie, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des Produits de Santé, Ouagadougou, Burkina Faso
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Département de la Biologie Médicale et de la Surveillance de la Maladie, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des Produits de Santé, Ouagadougou, Burkina Faso
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Département de la Biologie Médicale et de la Surveillance de la Maladie, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des Produits de Santé, Ouagadougou, Burkina Faso
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Département de Biologie Moléculaire, Hôpital Saint Camille de Ouagadougou, Ouagadougou, Burkina Faso
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Département des Laboratoires, Centre Hospitalier Universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso
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Département de la Biologie Médicale et de la Surveillance de la Maladie, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des Produits de Santé, Ouagadougou, Burkina Faso
,
Département de Biochimie-Microbiologie, Université Joseph KI-ZERBO, Ouagadougou, Burkina Faso
1 Département de Biochimie-Microbiologie, Université Joseph KI-ZERBO, Ouagadougou, Burkina Faso
2 Département de productions végétales, Centre Universitaire de Ziniaré, Ziniaré, Burkina Faso
3 Département de Biochimie-Microbiologie, Université Joseph KI-ZERBO, Ouagadougou, Burkina Faso
4 Département de Biochimie-Microbiologie, Université Joseph KI-ZERBO, Ouagadougou, Burkina Faso
5 Département de la Biologie Médicale et de la Surveillance de la Maladie, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des Produits de Santé, Ouagadougou, Burkina Faso
6 Département de la Biologie Médicale et de la Surveillance de la Maladie, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des Produits de Santé, Ouagadougou, Burkina Faso
7 Département de la Biologie Médicale et de la Surveillance de la Maladie, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des Produits de Santé, Ouagadougou, Burkina Faso
8 Département de Biologie Moléculaire, Hôpital Saint Camille de Ouagadougou, Ouagadougou, Burkina Faso
9 Département des Laboratoires, Centre Hospitalier Universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso
10 Département de la Biologie Médicale et de la Surveillance de la Maladie, Agence Nationale pour la Sécurité Sanitaire de l’Environnement, de l’Alimentation, du Travail et des Produits de Santé, Ouagadougou, Burkina Faso
11 Département de Biochimie-Microbiologie, Université Joseph KI-ZERBO, Ouagadougou, Burkina Faso
Introduction: The increasing incidence of urinary tract infections (UTIs) caused by multidrug-resistant organisms represents a pressing global health challenge. The current study aims to investigate longitudinal trends in antibiotic resistance among Enterobacteriaceae isolated from urine samples in Burkina Faso. Methods: A retrospective study was conducted at three medical laboratories in Burkina Faso over 6 years (January 1, 2017, to December 31, 2022). Data extracted from laboratory registers included patient demographics (age and sex), bacterial species identified, and antimicrobial susceptibility testing results. Results: Data from 5,310 positive patient urine cultures were extracted and analyzed in this study. Escherichia coli (67.12%) and Klebsiella pneumoniae (25.99%) were the predominant species. There was a marked increase in resistance to key antibiotic classes: amoxicillin resistance rose from 50.6% to 92.7%, ciprofloxacin from 43.2% to 60.2%, and third-generation cephalosporins from 36.0% to 53.4%. Multidrug resistance (MDR) prevalence increased from 80.9% to 92.1% over the study period. Conclusions: The study highlights a critical escalation in antimicrobial resistance among uropathogens in Burkina Faso. Incorporating local resistance data into empirical treatment guidelines and investing in diagnostic stewardship are essential to preserve treatment efficacy and prevent the spread of resistant strains.
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