Hypocholesterolemic and Growth Promoting Effects of <i>Lactobacillus plantarum</i> AK Isolated from a Nigerian Fermented Cereal Product on Rats Fed High Fat Diet — Oak Academic Publishing
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Hypocholesterolemic and Growth Promoting Effects of <i>Lactobacillus plantarum</i> AK Isolated from a Nigerian Fermented Cereal Product on Rats Fed High Fat Diet
Department of Biological Sciences, Faculty of Science, University of Abuja, Abuja, Nigeria
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Department of Biological Sciences, Faculty of Science, University of Abuja, Abuja, Nigeria
1 Department of Biological Sciences, Faculty of Science, University of Abuja, Abuja, Nigeria
2 Department of Biological Sciences, Faculty of Science, University of Abuja, Abuja, Nigeria
The hypocholesterolemic effect of Lactobacillus plantarum AK strain was tested in rats fed high cholesterol diet. The lipid profile, growth rate and microflora dynamics of rats that received L. plantarum AK strain were significantly different from the control group (p < 0.5). In particular low density lipoprotein was lower in serum of rats that received L. plantarum than those of the control group. The test group had a higher growth rate, higher lactobacilli counts but lower coliform and Escherichia coli counts over a period of 40 days and these observed differences were significant (p < 0.05). These results are indicative of the abilities of this strain to lower serum cholesterol levels as well as to improve intestinal microbial balance as observed in the microflora dynamics over a period of 40 days.
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