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Analytical and Stability Studies on Medical Cosmetics
Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
- 1 Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
- 2 Department of Analytical Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
American Journal of Analytical Chemistry·Volume 03 (2012)·Pages 277–281·Published 28 March 2012·DOI10.4236/ajac.2012.33037
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Abstract
Two simple and sensitive spectrofluorimetric (method Ι) and spectrophotometric (method ΙΙ) methods have been developed for the determination of some chloride containing toothpastes and panthenol-containing cosmetic preparations respectively. Method Ι is based on quantitative fluorescence quenching of (terbium-salicylate-hexamine ternary complex) by fluoride which could be measured at λem/λex of 547 nm/322 nm. The ΔF-concentration plot was rectilinear over the concentration range of 0.5 - 20 μg/ml. Method ΙΙ depends reaction of panthenol with nitrobenzoxadiazole chloride (NBD-Cl) and measuring the absorbance of the resultant product at 480 nm. The absorbance-concentration plot was rectilinear over the concentration range of 2 - 20 μg/ml.
KeywordsPanthenolSpectrophotometrySpectrofluorimetryStability Studies
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