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Experiments and Considerations through the Phase Diagram in Open Tubular Capillary Chromatography Based on Tube Radial Distribution of Ternary Mixed Solvents Using a Fused-Silica Capillary Tube
Department of Chemical Engineering and Materials Science, Faculty of Science and Engineering, Doshisha University, Kyotanabe, Japan
Department of Chemical Engineering and Materials Science, Faculty of Science and Engineering, Doshisha University, Kyotanabe, Japan
Department of Chemical Engineering and Materials Science, Faculty of Science and Engineering, Doshisha University, Kyotanabe, Japan
Department of Chemical Engineering and Materials Science, Faculty of Science and Engineering, Doshisha University, Kyotanabe, Japan
- 1 Department of Chemical Engineering and Materials Science, Faculty of Science and Engineering, Doshisha University, Kyotanabe, Japan
- 2 Department of Chemical Engineering and Materials Science, Faculty of Science and Engineering, Doshisha University, Kyotanabe, Japan
- 3 Department of Chemical Engineering and Materials Science, Faculty of Science and Engineering, Doshisha University, Kyotanabe, Japan
- 4 Department of Chemical Engineering and Materials Science, Faculty of Science and Engineering, Doshisha University, Kyotanabe, Japan
American Journal of Analytical Chemistry·Volume 03 (2012)·Pages 300–305·Published 17 April 2012·DOI10.4236/ajac.2012.34041
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Abstract
Capillary chromatography using an untreated open tubular capillary tube and a ternary solvent mixture consisting of water-hydrophilic/hydrophobic organic solvent as a carrier solution has been developed. The system is called tube radical distribution chromatography (TRDC). Separation performance of the TRDC system using a fused-silica capillary tube was examined through the phase diagram for the ternary water-acetonitrile-ethyl acetate solvent mixture. The TRDC system required homogeneous carrier solutions with solvent component ratios around the boundary curve between homogeneous and heterogeneous solution in the phase diagram. The data obtained using the fused-silica capillary tube were compared with those obtained using a polytetrafluoroethylene capillary tube in our previous study.
KeywordsOpen Tubular Capillary ChromatographyPhase DiagramFused-Silica Capillary TubeWater-Acetonitrile-Ethyl acetate MixtureTube Radial Distribution Phenomenon (TRDP)
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