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American Journal of Molecular Biology (AJMB) is an international journal dedicated to the latest advancements of molecular biology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas…
Suzana Makpol, Azalina Zainuddin, Kien Hui Chua
Human diploid fibroblasts (HDFs) undergo a limited number of cell divisions in culture. After certain population doublings, they reach a state of irreversible growth arrest known as replicative senescence. Senescent HDFs showed several molecular and cytologic…
Jeyalakshmi Kandhavelu, Meenakshisundaram Kandhavelu
Transcription, post-transcriptional modification, translation, post-translational modification, DNA replication, and signaling interaction of intra- and extra- cellular components are the relevant mechanisms in gene regulation. Transcription is one of the mos…
Simeon O. Kotchoni, Pacôme A. Noumavo, Adolphe Adjanohoun, Daniel P. Russo, John Dell’Angelo, Emma W. Gachomo, Lamine Baba-Moussa
The wild type maize genotype, B73, is not amenable for callus production and an efficient protocol for B73 maize callus induction has never been reported up-to-date. Scientific efforts in producing B73 maize callus using all known callus inducible media have…
Krishna Prakash, Pardeep Kumar, Pramod C. Rath
Interferon Regulatory Factor-2 (IRF-2) belongs to IRF family, was identified as a mammalian transcription factor involved in Interferon beta (IFN β ) gene regulation. Besides that IRF-2 is involved in immunomodulation, hematopoietic differentiation, cell cycl…
Usenobong F. Ufot, Monday I. Akpanabiatu
Manganese peroxidases (MnPs) are interesting enzymes in protein engineering, aimed at maximizing industrial bioprocesses such as lignin degradation and biofuel production. cDNA of the secreted short-type of MnP from Phlebia radiata (Pr-MnP3) has been successf…
David W. Dresser
Amh is a single copy gene which is expressed in different ways during mammalian development. Several potential promoter elements have been identified using physiological experimentation and on the basis of interspecific sequence comparison. The role of putati…
Eduardo Mere Del Aguila, Laidson Paes Gomes, Cristina Tristão Andrade, Joab Trajano Silva, Vânia Margaret Flosi Paschoalin
Chitosan has a unique chemical structure with high charge density, reactive hydroxyl and amino groups, and extensive hydrogen bonding. Chitin deacetylase (EC 3.5.1.41) catalyzes the hydrolysis of the N-acetamido groups of N-acetyl-D-glucosamine residues in ch…
Bilang Liu, Xiwu Qi, Qi Han, Ling Jia, Zhonghuai Xiang, Ningjia He
Melanization in insect hemolymph is triggered by the recognition of pathogen-associated molecular patterns via pattern recognition receptors. The signal transduction leads to the activation of the prophenoloxidase and hence the generation of melanin. The proP…
Tammy Lynne Silva, Angela Allard Cox, V. P. Boominathan, Peter Alan Jezewski, Tracie Lee Ferreira
Mutations in human TBX 22 cause X-linked cleft palate with anklyoglossia syndrome. The two zebrafish tbx 22 splice isoforms, tbx 22-1 and tbx 22-2, encode proteins of 444 and 400 amino acids, respectively. Zebrafish tbx 22 mRNA expression mirrors mammalian TB…
Xianyong Ma, Lin Wang, Jie Tang, Jie Li, Peter Ganins
Mint is a newly identified molecule that mediates signal transduction and modulates chromatin repression. Mint family members contain a highly conserved C-terminus SPOC domain (SpenParalog and OrthologsC-terminal domain) commonly associated with proliferation…
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American Journal of Molecular Biology (AJMB) is an international journal dedicated to the latest advancements of molecular biology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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