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American Journal of Molecular Biology (AJMB) is an international journal dedicated to the latest advancements of molecular biology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas…
Thomas Brillet, Michael C. Marden, Joanne I. Yeh, Tong-Jian Shen, Nancy T. Ho, Regina Kettering, Shoucheng Du, Corinne Vasseur, Elisa Domingues-Hamdi, Chien Ho, Véronique Baudin-Creuza
Octameric hemoglobins have been developed by the introduction of surface cysteines in either the alpha or beta chain. Originally designed as a blood substitute, we report here the structure and ligand binding function; in addition the interaction with haptogl…
Roderick Mallia, Jean-Paul Mangion, Christian Camenzuli, Annalisse Cassar, Paul Cacciottolo, John Cauchi, Joseph Borg, Sarfraz Ali, Pierre Schembri-Wismayer
The role of human papillomavirus in breast cancer pathogenesis is an area of considerable debate following differing results from all over the world. This study analyzed paraffin embedded tissue from 19 patients with benign or malignant breast disease. Standa…
Keli C. Fancher, Wei Hu
The Influenza A virus remains an annual and worldwide health concern due to its fast evolutionary rate. There are two major forms of Influenza evolution: drift, caused by mutations, and shift, which results from the exchange of genetic information between two…
Dechassa Duressa, Khairy M. Soliman, Robert W. Taylor, Dongquan Chen
It is well documented that aluminum (Al) toxicity is the most important constraint to crop production on acid soils and soybean is one of the most Al sensitive plant species. To advance our understanding of the molecular and genetic mechanisms of Al-tolerance…
Zhonglian Huang, Priyanka Surana, Daisuke Kihara, Richard Meilan, Keith Woeste
The economic value of a black walnut (<i>Juglans nigra</i> L.) tree is strongly determined by the quality and quantity of darkly colored heartwood in its stem. To understand the regulation of heartwood formation, we analyzed the region of heartwood formation…
Radhika Gaddipati, James D. West, James E. Loyd, Thomas Blackwell, Kirsten A. Lane, Nicole M. Lane, Kirk B. Lane
In this study, RLM-RACE was used to identify the transcriptional start site 387 bp upstream of the translational start. Evolutionarily conserved transcription factor binding sites were identified, and a series of luciferase reporter constructs driven by BMPR2…
Susumu Noguchi, Kazuyoshi Toyoshima, Soh Yamamoto, Toshio Miyazaki, Michiro Otaka, Sumio Watanabe, Katsunori Imai, Haruki Senoo, Ryoji Kobayashi, Mitsutoshi Jikei, Yasushi Kawata, Hiroshi Kubota, Hideaki Itoh
Cytosolic chaperonin CCT (also known as TRiC) is a hetero-oligomeric cage-like molecular chaperone that assists in protein folding by ATPase cycle-dependent conformational changes. However, role of the nucleo-tide binding and hydrolysis in CCT-assisted protei…
Aydın Rüstemoglu, Güvem Gümüs Akay, Halil Gürhan Karabulut, Ahmet Kadıkıran, Işık Bökesoy
This study is to survey 10 Y-STR loci in 241 males from Turkey. In this study, the 241 healthy and unrelated males living in different parts of Turkey for at least three generations were included. Genomic DNAs were isolated from peripheral blood samples by st…
Yuan De Tan, Myriam Fornage
To determine if genetic and environmental (dietary) factors and gene-environment interaction impact on the expression variation of genes related to stroke, we conducted microarray experiments using two homozygous rat strains SHRSR and SHRSP fed with high and…
Jayakishan K. Meher, Gananath N. Dash, Pramod Kumar Meher, Mukesh Kumar Raval
Development of efficient gene prediction algorithms is one of the fundamental efforts in gene prediction study in the area of genomics. In genomic signal processing the basic step of the identification of protein coding regions in DNA sequences is based on th…
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American Journal of Molecular Biology (AJMB) is an international journal dedicated to the latest advancements of molecular biology. The goal of this journal is to provide a platform for scientists and academicians all over the world to promote, share, and discuss various new issues and developments in different areas… All articles are open access under a CC BY 4.0 licence, with authors retaining copyright.
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