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Identification and Biological Activities of the Phenolic Compounds in <i>Eisenia arborea</i>
CEWIT Center for Systems Biology, The State University of New York, 119 Songdo Moonhwaro, Yeonsu-gu, Incheon, Korea
Baja Kelp Talasoterapia, Ensenada, Mexico
Department of Chemical and Biological Engineering, Hanbat National University, 125 Dongseodaero, Yuseong-gu, Daejeon, Korea
Department of Chemical and Biological Engineering, Hanbat National University, 125 Dongseodaero, Yuseong-gu, Daejeon, Korea
- 1 CEWIT Center for Systems Biology, The State University of New York, 119 Songdo Moonhwaro, Yeonsu-gu, Incheon, Korea
- 2 Baja Kelp Talasoterapia, Ensenada, Mexico
- 3 Department of Chemical and Biological Engineering, Hanbat National University, 125 Dongseodaero, Yuseong-gu, Daejeon, Korea
- 4 Department of Chemical and Biological Engineering, Hanbat National University, 125 Dongseodaero, Yuseong-gu, Daejeon, Korea
American Journal of Plant Sciences·Volume 12 (2021)·Pages 259–265·Published 24 February 2021·DOI10.4236/ajps.2021.122015
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Abstract
Four polyphenols were isolated and purified from a brown alga Eisenia arborea . These phlorotannin compounds showed strong radical scavenging and some enzyme inhibitory activities. All of the compounds showed strong antioxidative, acetylcholinesterase and butyrylcholinesterase inhibitory, and tyrosinase inhbibitory activities at 100 μg/mL. Dieckol and PFF inhibited butyrylcholinesterase, a new target for the treatment of Alzheimer’s disease, very strongly even at 10 μg/mL , more strongly than AChE. These two compounds also effectively inhibited tyrosinase. These results support the potential of developing natural antioxidants and antidementia agents from the brown alga.
Keywords<i>Eisenia arborea</i>Phenolic CompoundsDPPH Radical ScavengerEnzyme InhibitionIsolation
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