Profiling of Antifungal Activities from the Leaf Extract of Selected Apiaceae Family Plants against <i>Aspergillus fumigates</i> — Oak Academic Publishing
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Profiling of Antifungal Activities from the Leaf Extract of Selected Apiaceae Family Plants against <i>Aspergillus fumigates</i>
Department of Biochemistry and Biochemical Engineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, India
,
Centre of Energy and Environment Sustainability, Lucknow, India
,
Department of Biochemistry and Biochemical Engineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, India
1 Department of Biochemistry and Biochemical Engineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, India
2 Centre of Energy and Environment Sustainability, Lucknow, India
3 Department of Biochemistry and Biochemical Engineering, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, India
Many ethnic plants are used as a source of traditional medicine to cure a variety of illnesses in both humans and animals. Developing secondary metabolites in plants with antifungal characteristics, offer alternative medications for reasonably priced and safe treatments. In the present study, methanoli c, etha nolic, hexane and ethyl acetate leaves extracts of fifteen Apiaceae family plants were taken on the premise of their ethno botanical uses. The antifungal activ ity was assessed against significant fungal strain; Aspergillus fumigates by measuring minimum inhibitory concentration (MIC) and Zone of inhibition compared with standard drug fluconazole. Ethanol and methanol extracts of the plants were more effective than the hexane and ethyl acetate extracts against A. fumigates . Extracts of Cuminum cyminum, Pastinca sativa, Carum carvi, Dacus carota, Centella asiatica, Anthriscus cerefolium, Trachyspermum ammi, Pimpenella anisum and Apium graveolens showed relatively low inhibition effects between 3.5 to 8.5 mm. The MIC value of extracts was determined ranging between 0.8 to 0.43 μg/ml. The extract of Petroselinum cris pum , Foeniculum vulgare , Ferula assaefoetida , Bunium persicum, Anethum gra veolens and Coriander sativum could be considered as potential source of antifungal compounds for treating diseases in humans. Conclude remark s that these six extracts show astonishing fungicidal properties that can be used to discover drugs of very high potential.
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