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Effect of the Ethanolic Extract of Khaya senegalensis on Some Biochemical Parameters on Rabbit’s in Glucose Overload Condition
Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
Laboratoire de Biologie et de Typage moléculaire en Microbiologie Département de Biochimie et de Biologie Cellulaire, Université d’Abomey Calavi, Cotonou, Benin
Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
- 1 Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
- 2 Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
- 3 Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
- 4 Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
- 5 Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
- 6 Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
- 7 Laboratoire de Biologie et de Typage moléculaire en Microbiologie Département de Biochimie et de Biologie Cellulaire, Université d’Abomey Calavi, Cotonou, Benin
- 8 Laboratoire de Biomembranes et Signalisation Cellulaire Département de Physiologie Animale, Université d’Abomey-Calavi, Cotonou, Benin
American Journal of Plant Sciences·Volume 06 (2015)·Pages 240–248·Published 6 January 2015·DOI10.4236/ajps.2015.61027
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Abstract
The effect of the ethanolic extract Khaya senegalensis on some biochemical parameters was tested in rabbits with normal glucose and glucose overload. Phytochemical screening after three batches of 6 rabbits race (TBD) were treated with the extract in oral doses of respectively 10, 25 and 50 mg/kg body weight for 30 days; three other groups receiving respectively these doses of the extract were placed under a priori temporary overload of glucose; a control group received instead distilled water treatment. Blood glucose, triglycerides and total cholesterol were measured by spectrophotometry and weight gain of the animals was performed at the beginning of the experiment and every 2 weeks during the study period. The phytochemical screening revealed the presence of polyphenolic compounds (majority) of saponins of anthracene derivatives and steroids in the extract. The test results indicate that under the dose of 50 mg/kg body weight (BW) there was a significant decrease (p < 0.05) in blood glucose after 24 hours. The extract had no effect on the lipid profile or body weight of rabbits.
KeywordsRabbitKhaya senegalensisGlucoseLipid Profile
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