The essential oils from <i> Mentha viridis </i> (L). L. and <i> Mentha pulegium </i> L. were studied to assess their inhibitory potential on phospholipase from snake venoms and to determine their cytogenotoxic action on huma n cells. These essential oils were able to inhibit the breakdown of phospholipids induced by venoms of snakes of the <i> Bothrops </i> genus. Both oils presented hemolytic activity, although the <i> Mentha viridis </i> (L). L. oil induced hemolysis only at the highest concentrations (14.6 and 29 μL·mL - 1 ). The essential oil from <i> M. viridis </i> induced 3.9; 8.6 and 16.2 times greater damage to human leukocyte DNA than that observed with the positive control (100 μg · μL - 1 doxorubicin) at concentrations of 0.25; 0.5 and 1.0 μL · mL - 1 , respectively. A similar effect was observed for the oil from <i> M. pulegium </i> (2.1 , 2.5 and 15.8 times greater damage). The results extend the characterization of these essential oils and demonstrate their potential use in industries.
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