Clustering of the Values of a Response Variable and Simultaneous Covariate Selection Using a Stepwise Algorithm
- 1 Luxembourg Institute of Health, Strassen, Luxembourg
- 2 Institut Elie Cartan de Lorraine, University de Lorraine, CNRS UMR 7502, Vandoeuvre-lès-Nancy, France
- 3 INRIA, Projet BIGS, Vandoeuvre-lès-Nancy, France
- 4 CIC-P, CHRU, University Hospital, Nancy, France
Abstract
In supervised learning the number of values of a response variable can be very high. Grouping these values in a few clusters can be useful to perform accurate supervised classification analyses. On the other hand selecting relevant covariates is a crucial step to build robust and efficient prediction models. We propose in this paper an algorithm that simultaneously groups the values of a response variable into a limited number of clusters and selects stepwise the best covariates that discriminate this clustering. These objectives are achieved by alternate optimization of a user-defined model selection criterion. This process extends a former version of the algorithm to a more general framework. Moreover possible further developments are discussed in detail.
- Harrell, F.E. (2001) Regression Modeling Strategies: With Applications to Linear Models, Logistic Regression, and Survival Analysis. Springer Verlag. http://dx.doi.org/10.1007/978-1-4757-3462-1
- Flinterman, A.E., Knol, E.F., Lencer, D.A., Bardina, L., den Hartog Jager, C.F., Lin, J., et al. (2008) Peanut Epitopes for IgE and IgG4 in Peanut-Sensitized Children in Relation to Severity of Peanut Allergy. Journal of Allergy and Clinical Immunology, 121, 737-743. http://dx.doi.org/10.1016/j.jaci.2007.11.039
- Sauerbrei, W., Royston, P. and Binder, H. (2007) Selection of Important Variables and Determination of Functional Form for Continuous Predictors in Multivariable Model Building. Statistics in Medicine, 26, 5512-5528. http://dx.doi.org/10.1002/sim.3148
- Fan, J.Q. and Lv, J.C. (2010) A Selective Overview of Variable Selection in High Dimensional Feature Space. Statistica Sinica, 20, 101.
- Raftery, A.E. and Dean, N. (2006) Variable Selection for Model-Based Clustering. Journal of the American Statistical Association, 101, 168-178. http://dx.doi.org/10.1198/016214506000000113
- Fowlkes, E.B., Gnanadesikan, R. and Kettenring, J.R. (1988) Variable Selection in Clustering. Journal of Classification, 5, 205-228. http://dx.doi.org/10.1007/BF01897164
- Maugis, C., Celeux, G. and Martin-Magniette, M.L. (2009) Variable Selection for Clustering with Gaussian Mixture Models. Biometrics, 65, 701-709. http://dx.doi.org/10.1111/j.1541-0420.2008.01160.x
- Andrews, J.L. and McNicholas, P.D. (2013) Variable Selection for Clustering and Classification. Journal of Classification, 31, 136-153. http://dx.doi.org/10.1007/s00357-013-9139-2
- Collignon, O., Monnez, J.M., Vallois, P., Codreanu, F., Renaudin, J.M., Kanny, G., et al. (2011) Discriminant Analyses of Peanut Allergy Severity Scores. Journal of Applied Statistics, 38, 1783-1799. http://dx.doi.org/10.1080/02664763.2010.529878
- Jennrich, R.I. and Sampson, P.F. (1960) Stepwise Discriminant Analysis. Mathematical Methods for Digital Computers.
- Collignon, O. (2009) Recherche statistique de biomarqueurs du cancer et de l’allergie à l’arachide. PhD Thesis.
- Hosmer, D.W. and Lemeshow, S. (2000) Applied Logistic Regression. Vol. 354, Wiley-Interscience. http://dx.doi.org/10.1002/0471722146
- DeLong, E.R., DeLong, D.M. and Clarke-Pearson, D.L. (1988) Comparing the Areas under Two or More Correlated Receiver Operating Characteristic Curves: A Nonparametric Approach. Biometrics, 44, 837-845. http://dx.doi.org/10.2307/2531595