Contribution of Metabolic Imaging in the Exploration of Cognitive Disorders Related to COVID-19
- 1 Biophysics and Nuclear Medicine, Gaston Berger University, Saint-Louis, Senegal
- 2 ENT Department, Fann University Hospital, Dakar, Senegal
- 3 Biophysics and Nuclear Medicine, Cheikh Anta Diop University, Dakar, Senegal
- 4 Biophysics and Nuclear Medicine, Cheikh Anta Diop University, Dakar, Senegal
Abstract
On March 11, 2019, the WHO declared COVID-19 a pandemic disease. It is a respiratory tropism SARS COV 2 infection. In the emergency of the pandemic, in medical imaging, only computed tomography (CT) of the lungs was favored to assess lung lesions. In addition, many cases of post-COVID-19 cog nitive disorders have been reported. As the curve dips and services restart correctly, other imaging techniques have been used to better explore the dis ease. The objective of this presentation is to illustrate the contribution of metabolic imaging in the exploration of post COVID-19 cognitive disorders and to discuss the pathophysiological mechanisms. Hypometabolism brain lesions are objective signs of functional impairment whose pathophysiological mechanism is not yet fully understood. Metabolic imaging with PET-SCAN is a suitable tool for exploring these disorders, both for the severity and extent of the lesions and for the topography of the brain damage.
- Flis-Richard, H. and Verdonk, F. (2020) Atteintes neurologiques dans l’infection au SARS-CoV-2 (COVID-19). Le Praticien en Anesthésie Réanimation, 24, 186-189. https://doi.org/10.1016/j.pratan.2020.07.008
- Helms, J., Kremer, S., Merdji, H., Clere-Jehl, R., Schenck, M., Kummerlen, C., et al. (2020) Neurologic Features in Severe SARS-CoV-2 Infection. The New England Journal of Medicine, 382, 2268-2270. https://doi.org/10.1056/NEJMc2008597
- Liu, Y.-H., Chen, Y., Wang, Q.-H., et al. (2022) One-Year Trajectory of Cognitive Changes in Older Survivors of COVID-19 in Wuhan, China: A Longitudinal Cohort Study. JAMA Neurology, 79, 509-517. https://doi.org/10.1001/jamaneurol.2022.0461
- Taquet, M., Luciano, S., Geddes, J.R., et al. (2021) Bidirectional Associations between COVID-19 and Psychiatric Disorder: Retrospective Cohort Studies of 62 354 COVID-19 Cases in the USA. The Lancet Psychiatry, 8, 130-140. https://doi.org/10.1016/S2215-0366(20)30462-4
- Matsumoto, K. and Tanaka, K. (2004) Conflict and Cognitive Control. Science, 303, 969-970. https://doi.org/10.1126/science.1094733
- Penfiel, W. and Perot, P. (1963) The Brain’s Record of Auditory and Visual Experience. A Final Summary and Discussion. Brain, 86, 595-696. https://doi.org/10.1093/brain/86.4.595
- Vogt, B. (2009) Cingulate Neurobiology and Disease. Oxford University Press, Oxford. https://doi.org/10.1093/oso/9780198566960.001.0001
- Eustache, F. and Desgranges, B. (2014) La mémoire, les amnésies et les lobes frontaux. Revue de neuropsychologie, 6, 282-285. https://doi.org/10.3917/rne.064.0282
- Verger, A., Kas, A., Dudouet, P., et al. (2022) Visual Interpretation of Brain Hypometabolism Related to Neurological Long COVID: A French Multicentric Experience. European Journal of Nuclear Medicine and Molecular Imaging, 49, 3197-3202. https://doi.org/10.1007/s00259-022-05753-5