Objective : Online learning gained credit and acceptance among university students all over the world. COVID-19 outbrea k urged educational institutions to adopt that model of learning. A study conducted at Al-Quds univer sity in Jerusalem-Palestine among first, second, third, fourth- and fifth-academic year dental students aimed to evaluate their satisfaction on online learning. Academic year level was also assessed to investigate its effect on E-learning. Materials and Methods: The participants were 328 students (257 females, and 71 males) and their mean age was (20.5 years). A reliable and valid questionnaire was used to assess their perception levels regarding “perceived ease of use” (PEOU), “perceived usefulness” (PU), “perceived online education support service quality” (PSQ), and “online learning acceptance and student satisfaction (OLAS). Data were analyzed using factor analysis, structural equation model techniques, independent sample t-test and logistic regression. Results: Mean scores for the students on the questionnaire domains perceptions of online learning ranged from 2.14 (1.57) to 2.72 (1.70) on a 5-point scale. Cronbach’s alpha test is used to measure the reliability and internal consistency of the associated questionnaire domains, (Cronbach’s Alpha Based on Standardized Items > 0.896, and P value = 0 . 000 ) . Academic year level has significant ( P value = 0 . 000 ) effect on all questionnaire perceptions domains (PEU, PU, PSQ, and OLAS). Conclusions : Online education could be accepted among dental students in the clinical level of dental education (fourth and fifth years). First, second, and third dental year students (preclinical stages) didn’t accommodate and adopt E-learning technology. Expenses, COVID- 19 pandemic, facilities and logistics regarding E-learning could be factors related to what has been yielded in this study. Covid-19 pandamic might affect negatively on the results. Further research should be conducted to explore the value effectiveness of E-learning.
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