Research ArticleOpen AccessGoogle Scholar indexed
Antimicrobial Activity of Polyalthia longifolia (Sonn.) Thw. var. Pendula Leaf Extracts Against 91 Clinically Important Pathogenic Microbial Strains
- 1
- 2
Copy link · social · email
Abstract
The methanol, acetone and 1,4-dioxan fractions of leaves of Polyalthia longifolia (Sonn.) Thw. were evaluated for antibacterial and antifungal activity. 91 clinically important strains were used for the study which were both clinical isolates as well as identified strains. Piperacillin and gentamicin were used as standards for antibacterial assay, while nystatin and flucanazole were used as standards for antifungal assay. The antibacterial activity was more pronounced against gram positive bacterial and fungal strains. Poor activity was shown against gram negative bacterial strains studied.
KeywordsAntibacterialAntifungalPolyalthia longifoliaClinical IsolatesOrganic Solvent Extracts
- C. K. Amadou, “Promoting Alternative Medicine,” Africa Health Journal, 1998, Vol. 2, pp. 20-25.
- J. D. Hooker and C. B. Clarke, “Flora of British India, Vol. 1,” L. Reeve and Co. Ltd., London, 1875, pp. 1-741.
- K. Raghunathan and M. K. Mitra, “Pharmacognosy of Indigenous Drugs, Vol. 1,” Central Council for Research in Ayurveda and Siddha, New Delhi, 1985, pp. 127-139.
- S. K. Chakrabarti and B. Mukherjee, “Search for Anticancer Drug from Indian Medicinal Plants,” Indian Journal of Medical Research, Vol. 56, No. 4, 1968, pp. 445-455.
- K. Yamaguchi, H. Kinora, S. Natori, Ito, K. Nissbimoio, K. Bando, D. Mizuno and M. Ishignoo, “Screening Tests for Antitumor Activity of Asian Medicinal Herbs I,” Yakugaku Zashi, 1964, Vol. 84, pp. 373-377.
- K. R. Kirtikar and B. D. Basu, “Indian Medicinal Plants,” In: Annonaceae, 2nd Edition, Lalit Mohan Basu, Leader Road, Allahabad, India, Vol. 1, pp. 1993, pp. 72-73.
- C. M. Hasan, S. N. Islam and M. Ahsan, “Antibacterial Activity of Stem Bark of Polyalthia longifolia,” Dhaka University Studies, Part E, 1988, Vol. 4, pp. 63-66.
- A. W. Bauer, W. M. M. Kirby, J. C. Sherries and M. Truck, “Antibiotic Susceptibility Testing By Standard Single Disc Diffusion Method,” American Journal of Clinical Pathology, Vol. 45, No. 4, 1966, pp. 426-493.
- J. Parekh and S. Chanda, “Antibacterial and Phytochemical Studies on Twelve Species of Indian Medicinal Plants,” African Journal of Biomedical Research, Vol. 10, No. 2, 2007, pp. 175-181.
- M. J. Martinez, J. Betancourt, N. Alanso-Gonzalea and A. Jauregui, “Screening of Some Cuban Medicinal Plants for Antimicrobial Activity,” Journal of Ethnopharmacology, Vol. 52, No. 3, 1996, pp. 171-174.
- J. E. Loper, M. D. Henkels, R. G. Roberts, G. G. Grove, M. J. Willett and T. J. Smith, “Evaluation of Streptomycin, Oxytetracycline and Copper Resistance of Erwinia amylavora isolated from pear orchards in Washington State,” Plant Disease, Vol. 75, No. 3, 1991, pp. 287-290.
- J. Davis, “Inactivation of Antibiotics and Dissemination of Resistance Genes,” Science, Vol. 264, No. 5157, 1994, pp. 375-382.
- R. F. Service, “Antibiotics That Resist Resistance,” Science, Vol. 270, No. 5237, 1995, pp. 724-727.
- I. Ahmad, Z. Mehmood and F. Mohammad, “Screening of Some Indian Medicinal Plants for their Antimicrobial Properties,” Journal of Ethnopharmacology, Vol. 62, No. 2, 1998, pp. 183-193.