Hyperthermia for Breast Cancer Treatment Using Slotted Circular Patch Antenna
- 1 Electronic and Electrical Engineering, Tobruk University, Tobruk, Libya
- 2 Electronic and Electrical Engineering, Tobruk University, Tobruk, Libya
- 3 Electronic and Electrical Engineering, Tobruk University, Tobruk, Libya
- 4 Electronic and Electrical Engineering, Tobruk University, Tobruk, Libya
- 5 Electronic and Electrical Engineering, Tobruk University, Tobruk, Libya
Abstract
The primary intent of this paper is to investigate the potential of using a slotted circular patch antenna at 2.45 GHz for breast tumor hyperthermia treatment. A cancer treatment model consisting of a microstrip patch antenna and breast phantom comprising tumor is designed and simulated in CST Studio Suite 2018. The radiation properties of the proposed antenna attain 3 dB beam width of 74.1 ° and 70.5 ° for the E-Plane and the H-plane, respectively. The breast phantom is exposed to the designed antenna radiation for 10 minutes, leading to raise the breast phantom temperature by 8.5 ° C and 11.4 ° C once the antenna pumped power is 1.5 and 2 watt, respectively. By considering 10 minutes as an exposure time, the breast temperature as a function of the applied antenna power is studied and compared with previous published results.
- Dewey, W.C. (2009) Arrhenius Relationships from the Molecule and Cell to the Clinic. International Journal of Hyperthermia, 25, 3-20. https://doi.org/10.1080/02656730902747919
- Song, C.W.M., Shakil, A., Griffth, R.J. and Okajima, K. (1997) Improvement of Tumor Oxygenation Status by Mild Temperature Hyperthermia Alone or in Combination Carbonage. Semin Oncol, 24, 626632.
- Roemer, R.B. (1999) Engineering Aspects of Hyperthermia Therapy. Annual Review of Biomedical Engineering, 1, 347–376. https://doi.org/10.1146/annurev.bioeng.1.1.347
- Vorst, A.V., Rosen, A. and Kotsuka, Y. (2006) RF/Microwave Interaction with Biological Tissues. Vol. 1, John Wiley & Sons, Hoboken, NJ, 1-330. https://doi.org/10.1002/0471752053.ch
- Guo, B., Xu, L. and Li, J. (2005) Time Reversal Based Microwave Hyperthermia Treatment of Breast Cancer. The 39th Asilomar Conference on Signals, Systems and Computers, Pacific Grove, CA, 30 October-2 November 2005, 290-293.
- Bull, J.M., Scott, G.L., Strebel, F.R., et al. (2008) Fever-Range Whole-Body Thermal Therapy Combined with Cisplatin, Gemcitabine, and Daily Interferon-Alpha. International Journal of Hyperthermia, 24, 649-662. https://doi.org/10.1080/02656730802104740
- Zastrow, E., Hagness, S.C. and Van Veen, B.D. (2010) 3D Computational Study of Non-Invasive Patient-Specific Microwave Hyperthermia Treatment of Breast Cancer. Physics in Medicine and Biology, 55, 3611. https://doi.org/10.1088/0031-9155/55/13/003
- Trefna, H.D., Vrba, J. and Persson, M. (2010) Time-Reversal Focusing in Microwave Hyperthermia for Deep-Seated Tumors. Physics in Medicine and Biology, 55, 2167. https://doi.org/10.1088/0031-9155/55/8/004
- Asili, M., Chen, P., Hood, A.Z., Purser, A., Hulsey, R., Johnson, L. and Topsakal, E. (2015) Flexible Microwave Antenna Applicator for Chemo-Thermotherapy of the Breast. IEEE Antennas and Wireless Propagation Letters, 14, 1778-1781. https://doi.org/10.1109/LAWP.2015.2423655
- Nguyen, P.T., Abbosh, A. and Crozier, S. (2016) Three-Dimensional Microwave Hyperthermia for Breast Cancer Treatment in a Realistic Environment Using Particle Swarm Optimization. IEEE Transactions on Biomedical Engineering, 64, 1335-1344. https://doi.org/10.1109/TBME.2016.2602233
- Fiser, O., Merunka, I. and Vrba, J. (2015) Design, Evaluation and Validation of Planar Antenna Array for Breast Hyperthermia Treatment. 2015 Conference on Microwave Techniques (COMITE), Pardubice, 22-23 April 2015, 1-4. https://doi.org/10.1109/COMITE.2015.7120228