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Using Variations of Somatosensory Evoked Potentials to Quantify Spinal Cord Injury Level
Department of Electrical Engineering, American University of Sharjah, Sharjah, UAE
Department of Electrical Engineering, American University of Sharjah, Sharjah, UAE
Department of Neurology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, USA
Department of Neurology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, USA
Department of Neurology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, USA
- 1 Department of Electrical Engineering, American University of Sharjah, Sharjah, UAE
- 2 Department of Electrical Engineering, American University of Sharjah, Sharjah, UAE
- 3 Department of Neurology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, USA
- 4 Department of Neurology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, USA
- 5 Department of Neurology, Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, USA
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Abstract
Existing work indicates that the degree of variation of somatosensory evoked potential (SEP) signals between a healthy spinal pathway and spinal pathway affected by spinal cord injury (SCI) can be used to evaluate the integrity of the spinal pathway. This paper develops a metric that exploits the time-domain features of SEP signals (relative amplitude, time scaling, and time duration) in order to quantify the level of SCI. The proposed method is tested on actual SEP signals collected from rodents afflicted with focal demyelination SCI. Results indicate that the proposed method provides a robust assessment of the different degrees of demyelination in the spinal cord.
KeywordsSomatosensory Evoked Potential (SEP)Spinal Cord Injury (SCI)Signal Morphology
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