Research ArticleOpen AccessGoogle Scholar indexed
The Wall Shear Stress of a Pulsatile Blood Flow in a Patient Specific Stenotic Right Coronary Artery
Department of Mathematics Monmouth University West Long Branch, NJ, USA
- 1 Department of Mathematics Monmouth University West Long Branch, NJ, USA
Copy link · social · email
Abstract
A computer simulation of the blood flow in a patient specific atherosclerotic right coronary artery is carried out to study the blood flow pattern and the wall shear stress (WSS) distribution in the artery. Both temporal and special distribution patterns of the WSS of the non-Newtonian blood flow are presented and the regions on the lumen surface where the WSS is constantly lower than 1N/m2are identified.
KeywordsWall Shear StressStenotic Right Coronary ArteryNon-Newtonian
- C. G. Caro, J. M. Fitz-Gerald and R. C. Schroter, “Atheroma and Arterial Wall Shear Observation, Correlation and Proposal of a Shear-Dependent Mass Transfer Mechanism for Atherogenesis,” Proceedings of the Royal Society B: Biological Sciences, Vol. 177, 1971, pp. 109-159. http://dx.doi.org/10.1098/rspb.1971.0019
- M. H. Friedman., G. M. Hutchins, C. B. Bargeron, O. J. Deters and F. F. Mark, “Correlation between Intimal Thickness and Fluid Shear in Human Arteries,” Atherosclerosis, Vol. 39, 1981, pp. 425-436. http://dx.doi.org/10.1016/0021-9150(81)90027-7
- C. M. Gibson, L. Diaz, K. Kandarpa, F. M. Sacks, R. C. Pasternak, T. Sandor, et al., “Relation of Vessel Wall Shear Stress to Atherosclerosis Progression in Human Coronary Arteries,” Arteriosclerosis and Thrombosis, Vol. 13, 1993, pp. 310-315. http://dx.doi.org/10.1161/01.ATV.13.2.310
- D. N. Ku, D. P. Giddens, C. K. Zarins, et al, “Pulsatile Flow and Atherosclerosis in the Human Carotid Bifurcation: Positive Correlation between Plaque Location and Low and Oscillating Stress,” Arteriosclerosis, Vol. 5, 1985, pp. 292-302.
- D. N. Ku, “Blood Flow in Arteries,” The Annual Review of Fluid Mechanics, Vol. 29, 1997, pp. 399-434. http://dx.doi.org/10.1146/annurev.fluid.29.1.399
- R. M. Nerem and M. J. Levesque, “The Case for Fluid Dynamics as a Localizing Factor in Atherogenesis,” In: G. Schettler, R. M. Nerem, H. Schimid-Schronbein, H. Mori and C. Diehm, Eds., Fluid Dynamics as a Localizing Factor for Atherosclerosis, Springer-Verlag, Heidelberg, 1983, pp. 26-37. http://dx.doi.org/10.1007/978-3-642-69085-3_4
- C. K. Zarins, D. P. Giddens, B. K. Bharadvaj, V. S. Sottiurai, R. F. Mabon and S. Glagov, “Carotid Bifurcation Atherosclerosis: Quantitative Correlation of Plaque Localization with Flow Velocity Profiles and Wall Shear Stress,” Circulation Research, Vol. 53, 1983, pp. 502-514. http://dx.doi.org/10.1161/01.RES.53.4.502
- B. Liu and D. Tang, “Influence of Non-Newtonian Properties of Blood on the Wall Shear Stress in Human Atherosclerotic Right Coronary Arteries,” Molecular & Cellular Biomechanics, Vol. 8, No. 1, 2011, pp. 73-90.
- C. Yang, R. Bach, J. Zheng, I. El Naqa, P. K. Woodard, Z. Teng, K. Billiar and D. Tang, “In Vivo IVUS-Based 3D Fluid Structure Interaction Models with Cyclic Bending and Anisotropic Vessel Properties for Human Atherosclerotic Coronary Plaque Mechanical Analysis,” IEEE Transactions on Biomedical Engineering, Vol. 56, No. 10, 2009, pp. 2420-2428. http://dx.doi.org/10.1109/TBME.2009.2025658