The Effects of Camellia sinensis O. Ktze. Extract on Dynamic Vision—A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study
- 1 Toyo Shinyaku Co., Ltd., Saga, Japan
- 2 Toyo Shinyaku Co., Ltd., Saga, Japan
- 3 Toyo Shinyaku Co., Ltd., Saga, Japan
- 4 Toyo Shinyaku Co., Ltd., Saga, Japan
- 5 Toyo Shinyaku Co., Ltd., Saga, Japan
- 6 Toyo Shinyaku Co., Ltd., Saga, Japan
- 7 Toyo Shinyaku Co., Ltd., Saga, Japan
- 8 Nihonbashi Cardiology Clinic, Tokyo, Japan
Abstract
Background: The degradation of dynamic vision due to aging and visual display terminal (VDT) work is considered to significantly affect the quality of daily life. The intake of green tea containing epigallocatechin gallate (EGCG) has been reported to improve dynamic vision and is expected to prevent its decline. However, no clinical study has ever been conducted to evaluate green tea’s effect on dynamic vision in humans. Therefore, we aimed to evaluate the effects of a supplement containing green tea ( Camellia sinensis O. Ktze.) extract rich in EGCG on dynamic vision in humans. Methods: A randomized, double-blind, placebo-controlled, parallel-group study was conducted to evaluate the effects of Camellia sinensis O. Ktze. extract on dynamic vision in healthy participants. Forty healthy men and women were enrolled and randomly divided into an active group that consumed a supplement containing Camellia sinensis O. Ktze. extract (100 mg epigallocatechin gallate/day) for 6 weeks and a placebo group that consumed a supplement without the extract for the same period. The primary outcome was kinetic visual acuity (KVA). The secondary outcomes were the results of a questionnaire survey and a cognitive function test. Results: The active group showed a statistically significant improvement in KVA, compared to the placebo group ( P < 0.05). In addition, no adverse events attributable to the studied supplements were observed during the study period. Conclusions: These findings indicate that consuming supplements containing Camellia sinensis O. Ktze. extract may positively impact dynamic vision.
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