Production of Infant Formula Analogs by Membrane Fractionation of Caprine Milk: Effect of Temperature Treatment on Membrane Performance
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Abstract
A two-step-cascade membrane separation by ultrafiltration was performed on caprine milk prepared under different temperature conditions to eliminate beta-lactoglobulin (β-Lg) from the whey fraction. Effects of temperature treatment and membrane pore size on the elimination of β-Lg and retention of alpha-lactalbumin (α-La) were examined to determine the optimum permeate fraction for production of infant formula analogues from caprine milk. The frozen raw caprine milk, with and without prior pasteurization, showed the best membrane separation performance. The permeates obtained from the 800/30kDa membrane combination showed the optimal results. The infant formula analog produced using the casein and 800/30kDa-permeate fractions of the treated caprine milk had the closest similarity to human milk with respect to the total protein content (1.3g 100g<sup>-1</sup>), beta-lactoglobulin content (1% - 2%), and casein- α-lactalbumin ratio (0.6 - 0.7). Membrane performance during ultrafiltration of caprine milk was affected by temperature treatment of the milk prior to membrane separation.
- A. H. Rosenblum and P. Rosenblum, “Gastrointestinal Allergy in Infancy: Significance of Eosinophiles in the Stools,” Pediatrics, Vol. 9, No. 3, 1952, pp. 311-319.
- Y. W. Park, “Hypo-Allergenic and Therapeutic Significance of Goat Milk,” Small Ruminant Research Journal, Vol. 14, No. 2, 1994, pp. 151-159. doi:10.1016/0921-4488(94)90105-8
- Y. W. Park and G. F. W. Haenlein, “Therapeutic and Hypoallergenic Values of Goat Milk and Implication of Food Allergy,” In: Y. W. Park and G. F. W. Haenlein, Eds., Handbook of Milk of Nonbovine Mammals, Blackwell Publishing Professional, Oxford, 2006, pp. 121-136.
- L. S. Taitz and B. L. Armitage, “Goat’s Milk for Infants and Children,” British Medical Journal, Vol. 288, 1984, pp. 428-429. doi:10.1136/bmj.288.6415.428
- J. A. Birkbeck, “Goat Milk in Infant Feeding,” New Zealand Medical Journal, Vol. 87, 1978, pp. 365-369.
- P. Kirke, “Human Consumption of Goat’s Milk,” International Medical Journal, Vol. 72, 1979, pp. 492-498.
- V. B. Walker, “Therapeutic Uses of Goat Milk in Modern Medicine,” British Goat Society’s Yearbook 24 - 26, 1965, pp. 23-26.
- G. F. W. Haenlein and R. Caccese, “Goat Milk versus Cow Milk,” In: G. F. W. Haenlin and D. L. Ace, Eds., Extension Goat Handbook, USDA Publication, Washington DC, 1984, pp. 1-4.
- Y. W. Park and H. I. Chukwu, “Macro-Mineral Concentrations in Milk of Two Goat Breeds at Different Stages of Lactation,” Small Ruminant Research Journal, Vol. 1, No. 2, 1988, pp. 157-166. doi:10.1016/0921-4488(88)90032-6
- Y. W. Park, “Relative Buffering Capacity of Goat Milk, Cow Milk, Soy-Based Infant Formulas, and Commercial Non-Prescription Antacid Drugs,” Journal of Dairy Science, Vol. 74, No. 10, 1991, pp. 3326-3333. doi:10.3168/jds.S0022-0302(91)78520-2
- S. L. Bahner and D. C. Heiner, “Allergies to Milk,” Grune and Stratton Publishing, New York, 1980.
- M. Heyman and J. F. Desjeux, “Significance of Intestinal Food Protein Transport,” Journal of Pediatric, Gastroenterology, Nutrition, Vol. 15, No. 1, 1992, pp. 48-57. doi:10.1097/00005176-199207000-00008
- Y. W. Park, “Goat Milk-Chemistry and Nutrition,” In: Y. W. Park and G. F. W. Haenlein, Eds., Handbook of Milk of Nonbovine Mammals, Blackwell Publishing Professional, Oxford, 2006, pp. 34-58.
- S. Parkash and R. Jenness, “The Composition and Characteristics of Goat’s Milk: A Review,” Dairy Science Abstract, Vol. 30, 1968, p. 67.