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Antiproliferative Activity of “<i>Lycopersicon esculentum</i>” Leaves (Var. Paul Robenson): Preliminary Study
Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084, Fisciano, Italy
Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084, Fisciano, Italy
Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084, Fisciano, Italy
Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084, Fisciano, Italy
Council of National Research (CNR)—Institute of Biomolecular Chemistry, Pozzuoli, Italy
Council of National Research (CNR)—Institute of Biomolecular Chemistry, Pozzuoli, Italy
Council of National Research (CNR)—Institute of Biomolecular Chemistry, Pozzuoli, Italy
- 1 Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084, Fisciano, Italy
- 2 Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084, Fisciano, Italy
- 3 Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084, Fisciano, Italy
- 4 Department of Pharmaceutical Sciences, University of Salerno, Via Ponte Don Melillo 84084, Fisciano, Italy
- 5 Council of National Research (CNR)—Institute of Biomolecular Chemistry, Pozzuoli, Italy
- 6 Council of National Research (CNR)—Institute of Biomolecular Chemistry, Pozzuoli, Italy
- 7 Council of National Research (CNR)—Institute of Biomolecular Chemistry, Pozzuoli, Italy
Food and Nutrition Sciences·Volume 04 (2013)·Pages 632–635·Published 5 June 2013·DOI10.4236/fns.2013.46081
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Abstract
Among plants, the Lycopersicon esculentum (Solanaceae) is the most important for its beneficial effects on health. Several epidemiological studies have shown the benefits of tomato consumption in the cancer and cardiovascular disease prevention. Tomato products constitute the major source of lycopene, the most potent antioxidant among carotenoids in vitro . In tomatoes leaves are also present many secondary metabolites including phenolic compounds, phytoalexins, protease inhibitors and glycoalkaloids who protect against adverse effects of hosts including fungi, bacteria, viruses, and insects and are involved in host-plant resistance. In this work we evaluated the antiproliferative activity of tomato leaves extract (var. Paul Robenson) in vitro .
Keywords<i>Lycopersicon esculentum</i>Antiproliferative ActivityGlioma Cell Line
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