Preliminary Evaluations of a Complex Amino Acid Supplement, Fatigue Reviva<sup>TM</sup>, to Reduce Fatigue in a Group of Professional Male Athletes and a Group of Males Recruited from the General Public
- 1 School of Environmental and Life Sciences, University of Newcastle, Newcastle, Australia.
- 2 School of Environmental and Life Sciences, University of Newcastle, Newcastle, Australia.
- 3 School of Environmental and Life Sciences, University of Newcastle, Newcastle, Australia.
- 4 School of Environmental and Life Sciences, University of Newcastle, Newcastle, Australia.
Abstract
Fatigue Reviva TM was developed to provide a source of amino acids for rapid uptake by the body while avoiding the need for digestion of proteins. Complex amino acid formulations have significant palatability issues and thus new products require significant development and testing. An initial pilot study with 18 professional male athletes and 21 males recruited from the general public was undertaken to evaluate product palatability and tolerance over a 30 day period. This investigation found that Fatigue Reviva TM was well tolerated in terms of palatability and usage across 39 participants with only two of the 39 subjects reporting an issue with taste and five reporting an issue with flatulence. The professional athlete cohort reported a significantly lower level of fatigue compared with the general public group prior to commencement of supplementation. The general public group reported a significant reduction in fatigue following the use of Fatigue Reviva TM over the 30 - day period. Compliance was extremely poor amongst the professional athlete group and as a result, changes in fatigue could not be statistically assessed for this group over the study period. Preliminary assessment of the product indicated that it has the potential to significantly reduce fatigue. Minor modifications to the product were identified for future development.
- T. Roberts, “Sub-Health: The Chronic Catabolic State and the Possible Role of Chronic Infection,” Australian Universities International Alumni Convention, 2007. http://wenku.baidu.com/view/dc0ec9ef0975f46527d3e19a.html
- R. H. Dunstan, D. L. Sparkes, M. M. Macdonald, T. K. Roberts, C. Wratten, M. B. Kumar, S. Baines, J. W. Denham, S. A. Gallagher and T. Rothkirch, “Altered Amino Acid Homeostasis and the Development of Fatigue by Breast Cancer Radiotherapy Patients: A Pilot Study,” Clinical Biochemistry, Vol. 44, No. 2-3, 2011, pp. 208215. http://dx.doi.org/10.1016/j.clinbiochem.2010.10.002
- S. N. Niblett, K. E. King, R. H. Dunstan, P. Clifton-Bligh, L. A. Hoskin, T. K. Roberts, G. R. Fulcher, N. R. McGregor, H. L. Butt, I. Klineberg and T. B. Rothkirch, “Hematologic and Urinary Excretion Anomalies in Patients with Chronic Fatigue Syndrome,” Experimental Biology and Medicine, Vol. 232, No. 8, 2007, pp. 1041-1049. http://dx.doi.org/10.3181/0702-RM-44
- R. H. Dunstan, N. R. McGregor, H. L. Butt, T. K. Roberts, I. J. Klineberg, S. H. Niblett, T. Rothkirch and I. Buttfield, “Characterization of Differential Amino Acid Homeostasis amongst Population Subgroups: A Basis for Determining Specific Amino Acid Requirements,” Journal of Nutritional and Environmental Medicine, Vol. 10, No. 3, 2000, pp. 211-223. http://dx.doi.org/10.1080/13590840050134881
- Australian Government, “Australian New Zealand Food Standards Codes,” 2013. http://www.comlaw.gov.au/Search/Australia%20New%20Zealand%20Food%20Standards
- New South Wales Government, “Food Act 2003 No 43,” 2013. http://www.legislation.nsw.gov.au/viewtop/inforce/act+43+2003+FIRST+0+N/
- New South Wales Government, “Food Regulation 2010,” 2013. http://www.legislation.nsw.gov.au/viewtop/inforce/subordleg+250+2010+cd+0+N
- T. Chalder, G. Berelowitz, T. Pawlikowska, L. Watts, S. Wessely, D. Wright and E. P. Wallace, “Development of a Fatigue Scale,” Journal of Psychosomatic Research, Vol. 37, No. 2, 1993, pp. 147-153. http://dx.doi.org/10.1016/0022-3999(93)90081-P
- S. J. M. Ten Bruggencate, I. M. J. Bovee-Oudenhoven, M. L. G. Lettink-Wissink, M. B. Katan and R. van der Meer, “Dietary Fructooligosaccharides Affect Intestinal Barrier Function in Healthy Men,” Journal of Nutrition, Vol. 136, No. 8, 2006, pp. 70-74.
- C. C. Roy, C. L. Kien, L. Bouthillier and E. Levy, “ShortChain Fatty Acids: Ready for Prime Time?” Nutrition in Clinical Practice, Vol. 21, No. 4, 2006, pp. 351-366. http://dx.doi.org/10.1177/0115426506021004351