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Effect of Microwave Irradiation on Oximation of Acetylferrocene
Department of Applied Chemistry, Ritsumeikan University, Shiga, Japan
Department of Applied Chemistry, Ritsumeikan University, Shiga, Japan
- 1 Department of Applied Chemistry, Ritsumeikan University, Shiga, Japan
- 2 Department of Applied Chemistry, Ritsumeikan University, Shiga, Japan
Green and Sustainable Chemistry·Volume 11 (2021)·Pages 1–8·Published 2 February 2021·DOI10.4236/gsc.2021.111001
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Abstract
Microwave-assisted reactions are an environmentally friendly approach for synthesizing organic compounds. In this study, oximation of acetylferrocene and acetophenone was conducted under both microwave irradiation and conventional heating conditions. Acetylferrocene and acetophenone were subjected to oximation under the two conditions in various solvent mixtures, and the extent of conversion was determined by 1 H nuclear magnetic resonance spectroscopy. Microwave irradiation was found to accelerate the rate of oximation of both acetylferrocene and acetophenone. Acceleration of the reaction under microwave irradiation was attributed to the efficient absorption of microwaves by the ferrocene nucleus.
KeywordsMicrowave IrradiationConventional HeatingFerrocene NucleusAcetophenoneAcetylferroceneOximation
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