Bismuth (III) Triflate Catalyzed Multicomponent Synthesis of 2,4,5-Trisubstituted Imidazoles — Oak Academic Publishing
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Bismuth (III) Triflate Catalyzed Multicomponent Synthesis of 2,4,5-Trisubstituted Imidazoles
Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
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Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
,
Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
,
Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
,
Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
,
Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
,
Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
1 Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
2 Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
3 Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
4 Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
5 Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
6 Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
7 Laboratory for Environmentally Friendly Organic Synthesis, Department of Chemistry & Biochemistry, Illinois Wesleyan University, Bloomington, IL, USA
Substituted imidazoles are of interest because of their useful biological activities. While several methods have been developed for the synthesis of such compounds, some of the reported methods utilize corrosive or toxic catalysts. We report a bismuth (III) triflate catalyzed multicomponent synthesis of 2,4,5-trisubstituted imidazoles. Bismuth (III) compounds are attractive from a green chemistry perspective because they are remarkably non-toxic and non-corrosive. Multicomponent syntheses save time and generate less waste.
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