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Resolution of Alcohol Racemate by Oil
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Green and Sustainable Chemistry·Volume 01 (2011)·Pages 7–11·Published 25 February 2011·DOI10.4236/gsc.2011.11002
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Abstract
Vegetable oil was successfully used as solvent and acyl donor in the kinetic resolution of several secondary alcohol racemates yielding high enantioselectivities. Using vegetable oil as solvent and acyl donor allowed easy separation of the pure alcohol enantiomer by extraction with methanol, by distillation under reduced pressure, or by column chromatography.
KeywordsOilKinetic ResolutionLipaseSeparation
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