Solvent-Free Synthesis of Carboxylic Acids and Amide Analogs of CAPE (Caffeic Acid Phenethyl Ester) under Infrared Irradiation Conditions — Oak Academic Publishing
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Solvent-Free Synthesis of Carboxylic Acids and Amide Analogs of CAPE (Caffeic Acid Phenethyl Ester) under Infrared Irradiation Conditions
Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
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Departamento de Biología celular, Centro de Investigación y Estudios Avanzados, Instituto Politécnico Nacional, México, D.F., México
,
Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
,
Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
,
Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
,
Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
,
Qsar Analytics S.A. de C.V. Ciudad Satélite, Naucalpan de Juárez, México
,
Departamento de Biología celular, Centro de Investigación y Estudios Avanzados, Instituto Politécnico Nacional, México, D.F., México
,
Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
1 Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
2 Departamento de Biología celular, Centro de Investigación y Estudios Avanzados, Instituto Politécnico Nacional, México, D.F., México
3 Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
4 Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
5 Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
6 Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
7 Qsar Analytics S.A. de C.V. Ciudad Satélite, Naucalpan de Juárez, México
8 Departamento de Biología celular, Centro de Investigación y Estudios Avanzados, Instituto Politécnico Nacional, México, D.F., México
9 Laboratorio de Química Medicinal y Teórica, Departamento de Ciencias Químicas, FES Cuautitlán, Universidad Nacional Autónoma de México, Cuautitlán Izcalli, México
A convenient and easy method is described for the formation of carboxamides from carboxylic acids and primary amines in solventless conditions using infrared (IR) light. Thus, under IR light, cinnamic acid derivatives and amines can produce yields ranging from 50% to 85% of the resulting amide.
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