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Microwave Irradiation Effect on Intermolecular and Intramolecular Friedel-Crafts Acylation Reaction
Department of Applied Chemistry, Ritsumeikan University, Shiga, Japan
Department of Applied Chemistry, Ritsumeikan University, Shiga, Japan
- 1 Department of Applied Chemistry, Ritsumeikan University, Shiga, Japan
- 2 Department of Applied Chemistry, Ritsumeikan University, Shiga, Japan
Green and Sustainable Chemistry·Volume 10 (2020)·Pages 18–23·Published 21 January 2020·DOI10.4236/gsc.2020.101002
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Abstract
The effect of microwave irradiation on the intermolecular and intramolecular Friedel - Crafts acylation of aromatic compounds was investigated. Microwave irradiation had no effect on the intermolecular reaction but had an accelerating effect on the intramolecular reaction. This enhanced intramolecular reactivity that was attributed to the high probability of close proximity between the reaction sites.
KeywordsMicrowave Irradiation EffectFriedel-Crafts ReactionCyclization
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