Retro-Viral Disease Status of Patients on DOTS Tuberculosis Treatment Strategy in a South-East Nigeria Teaching Hospital
- 1 Department of Community Medicine, University of Nigeria, Enugu, Nigeria
- 2 Department of Community Medicine, University of Nigeria, Enugu, Nigeria
- 3 Department of Business Administration, Enugu State University of Science & Technology, Enugu, Nigeria
- 4 Tricity Health Care, LLC, Tx., USA
- 5 Department of Community Medicine, University of Nigeria, Enugu, Nigeria
- 6 Department of Community Medicine, University of Nigeria, Enugu, Nigeria
Abstract
Introduction: Tuberculosis is associated with HIV/AIDS and it has been recognized as one of the most frequent opportunistic infections in persons with HIV. Tuberculosis is the leading cause of death in people with HIV having an adverse effect on HIV progression. Objectives: The objective is to determine the retroviral disease status of patients on the DOTS strategy. Materials and Methods: A retrospective study of patients was seen at the University of Nigeria Teaching Hospital from January 2013 to April 2015. Relevant information was collected from patients’ folders. Statistical analysis was done with the SPSS and results were represented in tables. Results: 171 patients (77%) were HIV negative while 51 (23%) were positive giving an HIV negative/HIV positive ratio of 3.35:1. 97 patients (43.7%) had 6 months duration of treatment. The least was 2 patients (0.9%) that complied with their medication for 7 months. The 61 - 70 years age group accounted for the least number of HIV-positive patients. Conclusion/Recommendations: There is strong tuberculosis/HIV co-infectivity among the studied population. Strategies to reduce the burden of TB/HIV co-infection should be strengthened.
- World Health Organization (WHO) (1996) Group at Risk. WHO’s Report on the Tuberculosis Epidemics. WHO, Geneva.
- World Health Organization (WHO) (2008) Global Tuberculosis Control. WHO Report, Geneva.
- Okeke, T.A. and Aguwa, E.N. (2006) Evaluation of the Implementation of Directly Observed Treatment Short Course by Private Medical Practitioners in the Management of Tuberculosis in Enugu. Nigeria Tanzania Health Research Bulletin, 8, 86-89.
- Okuonghae, D. and Korobeinikov, A. (2007) Dynamics of Tuberculosis: The Effect of Direct Observation Therapy Strategy (DOTS) in Nigeria. Mathematical Modelling of Natural Phenomena, 2, 101-113.
- World Health Organization (WHO) (1994) Framework for Effective Tuberculosis Control. WHO, Geneva.
- Idoko, C.A., Idoko, C.I. and Chidolue, I.C. (2019) Attitude of Women in a Nigerian Local Government to Reproductive Health Following Health Education Intervention. African Health Sciences, 19, 3018-3026. https://doi.org/10.4314/ahs.v19i4.23
- Idoko, C.A., Omotowo, I.B., Agunwa, C.C., Okeke, C., Obi, I.E., Ndu, A.C., Ekwueme, O.C., Uzochukwu, B.S.C. and Onwujekwe, O. (2017) Effect of Health Education on Reproductive Health Knowledge of Women in Two Local Government Areas, South East Nigeria, a Cross-Sectional Study. International Journal of Medicine and Health Development, 22, 130-137.
- Dim, C.C., Dim, N.R. and Morkve, O. (2011) Tuberculosis: A Review of Current Concepts and Control Programme in Nigeria. Nigerian Journal of Medicine, 20, 200-206.
- Park, K. (2004) Park’s Textbook of Preventive and Social Medicine. 18th Edition, M/S Banarsidas Bhanot, Jabalpur, 131-140.
- Omotowo, B.I., Itanyi, I., Ndibuaagu, E.O., Agunwa, C.A., Obi, I.E., Idoko, C.A. and Ndu, A.C. (2019) Comparative Study of Six-Month and Eight-Month Treatment of New Smear Positive Tuberculosis Cases at a Tertiary Health Facility in Enugu, South-Eastern Nigeria. International Journal of Medicine and Health Development, 24, 78-84. https://doi.org/10.4103/ijmh.IJMH_24_19
- Amoran, O.E., Osiyale, O.O. and Lawal, K.M. (2011) Pattern of Default among Tuberculosis Patients on Directly Observed Therapy in Rural Primary Health Care Centres in Ogun State, Nigeria. Journal of Infectious Diseases and Immunity, 3, 90-95.
- Rajasekaran, S., Mahilmaran, A., Annadural, S., Kumar, S. and Raja, K. (2007) Manifestation of Tuberculosis in Patients with Human Immunodeficiency Virus. A Large Indian Study. Annals of Thoracic Medicine, 2, 58-60. https://doi.org/10.4103/1817-1737.32231