This narrative review explores the synergistic anti-inflammatory mechanisms of acupuncture and stretching. Acupuncture induces mechanical forces that activate neuro-immune pathways, modulating immune cell functions and enhancing anti-inflammatory cytokine secretion. Through tissue tension, stretching promotes fibroblast activity and macrophage polarization, further amplifying anti-inflammatory responses. Together, these interventions strengthen macrophage activity, accelerate tissue repair, and improve treatment outcomes for chronic inflammation, sports injuries, and cancer recovery. This review consolidates experimental evidence to provide a theoretical basis for advancing research into fascial acupuncture and its clinical applications.
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