Today nanoparticles based drug delivery or imaging agents are extremely being investigated as a very powerful tool in early diagnostics or treatment of different kinds of cancers including prostate malignancies. Among the diverse developing nanomaterials, biocompatible biodegradable dendrimers and chitosan or PLGA (Poly Lactic-co-Glycolic Acid) derivatives are more considered due to their safer profiles. As a result, finding novel prostate imaging agents based on nano sized structures would be of high global interest which will be further discussed in this review.
KeywordsPLGADendrimerNanoparticles Based Drug Delivery or Imaging AgentsProstate Malignancies
Lin, W., et al. (2009) Magnetic Nanoparticles for Early Detection of Cancer by Magnetic Resonance Imaging. MRS Bulletin, 34, 441-448. http://dx.doi.org/10.1557/mrs2009.120
Sun, C., et al. (2008) Magnetic Nanoparticles in MR Imaging and Drug Delivery. Advanced Drug Delivery Reviews, 60, 1252-1265. http://dx.doi.org/10.1016/j.addr.2008.03.018
Reddy, J.M. and Prasad, V. (2005) Step by Step MRI. 3rd Edition, Jaypee Brothers, New Delhi, 124-125. http://dx.doi.org/10.5005/jp/books/10844
Sasaki, M., et al. (2005) Enhancement Effects and Relaxivities of Gadolinium-DTPA at 1.5 versus 3 Tesla: A Phantom Study. Magnetic Resonance in Medical Sciences, 4, 145-149. http://dx.doi.org/10.2463/mrms.4.145
Raymond, K.N. and Pierre, V.C. (2005) Next Generation, High Relaxivity Gadolinium MRI Agents. Bioconjugate Chemistry, 16, 3-8. http://dx.doi.org/10.1021/bc049817y
Moriggi, L.C. (2009) Gold Nanoparticles Functionalized with Gadolinium Chelates as High-Relaxivity MRI Contrast Agents. Journal of the American Chemical Society, 131, 10828-10829. http://dx.doi.org/10.1021/ja904094t
Wai-Yan, C. and Wing-Tak, W. (2007) Small Molecular Gadolinium (III) Complexes as MRI Contrast Agents for Diagnostic Imaging. Coordination Chemistry Reviews, 251, 2428-2451. http://dx.doi.org/10.1016/j.ccr.2007.04.018
Shahbazi-Gahrouei, D., et al. (2001) In Vivo Studies of Gd-DTPA-Monoclonal Antibody and Gd-Porphyrins: Potential Magnetic Resonance Imaging Contrast Agents for Melanoma. Journal of Magnetic Resonance Imaging, 14, 169-174. http://dx.doi.org/10.1002/jmri.1168
Amanluo, M., et al. (2011) Gd3+-DTPA-DG: Novel Nanosized Dual Anticancer and Molecular Imaging Agent. International Journal of Nano-medicine, 6, 747-763.
Ananta, J.S., et al. (2010) Geometrical Confinement of Gadolinium-Based Contrast Agents in Nanoporous Particles Enhances T1 Contrast. Nature Nanotechnology, 5, 815-821. http://dx.doi.org/10.1038/nnano.2010.203
Shahbazi-Gahrouei, D., Roufeh, M. and Tavakoli, M.B. (2006) Gadolinium-Diethylenetriaminepenta-Acetic Acid Con- jugated with Monoclonal Antibody C595 as New Magnetic Resonance Imaging Contrast Agents for Breast Cancer (MCF-7) Detection. Iranian Biomedical Journal, 10, 209-213.
McNeil, S.E. (2005) Nanotechnology for the Biologist. Journal of Leukocyte Biology, 78, 585-594. http://dx.doi.org/10.1189/jlb.0205074
Dubey, P.K., Mishra, V., Jain, S., Mahor, S. and Vyas, S.P. (2004) Liposomes Modified with Cyclic RGD Peptide for Tumor Targeting. Journal of Drug Targeting, 12, 257-264. http://dx.doi.org/10.1080/10611860410001728040
Vandamme, T.F. and Brobeck, L. (2005) Poly(Amidoamine) Dendrimers as Ophthalmic Vehicles for Ocular Delivery of Pilocarpine Nitrate and Tropicamide. Journal of Controlled Release, 102, 23-38. http://dx.doi.org/10.1016/j.jconrel.2004.09.015
Yang, W., Barth, R.F., Wu, G., Bandyopadhyaya, A.K., Thirumamagal, B.T., Tjarks, W., Binns, P.J., Riley, K., Patel, H., Coderre, J.A., Ciesielski, M.J. and Fenstermaker, R.A. (2004) Boronated Epidermal Growth Factor as a Delivery Agent for Neutron Capture Therapy of EGF Receptor-Positive Gliomas. Applied Radiation and Isotopes, 61, 981-985. http://dx.doi.org/10.1016/j.apradiso.2004.05.071
Hamedy, S., Haddadi, A., Hung, R.W. and Lavasanifar, A. (2011) Targeting Dendritic Cells with Nano-Particulate PLGA Cancer Vaccine Formulation. Advance Drug Delivery Reviews, 63, 943-955. http://dx.doi.org/10.1016/j.addr.2011.05.021
Hasan, W., Chu, K., Gullapalli, A., Dunn, S.S., Enlow, E.M., Luft, J.C., Tian, S.M., Napier, M.E., Pohlhaus, P.D., Rolland, J.P. and DeSimone, J.M.(2012). Delivery of Multiple siRNAs Using Lipid-Coated PLGA Nanoparticles for Treatment of Prostate Cancer. Nano Letters, 12, 287-292. http://dx.doi.org/10.1021/nl2035354
Burtea, C., Laurent, S., Colet, J.M., Vander, E.L. and Muller, R.N. (2003) Development of New Glycosylated Derivatives of Gadolinium Diethylenetriaminepentaacetic for Magnetic Resonance Angiography. Investigative Radiology, 38, 320-333. http://dx.doi.org/10.1097/01.RLI.0000066251.65982.e6
Ganapathy, V., Thangaraju, M. and Prasad, P.D. (2009) Nutrient Transporters in Cancer: Relevance to Warburg Hypothesis and Beyond. Pharmacology & Therapeutics, 121, 29-40. http://dx.doi.org/10.1016/j.pharmthera.2008.09.005
Ardestani, M.S., et al. (2010) Novel and Facile Methods for the Synthesis of DTPA-Mono-Amide: A New Completely Revised Strategy in Radiopharmaceutical Chemistry. Journal of Radioanalytical and Nuclear Chemistry, 283, 447-455. http://dx.doi.org/10.1007/s10967-009-0414-y
Shen, Z.Y., Li, Y., Kohama, K., Oneill, B. and Bi, J.X. (2011) Improved Drug Targeting of Cancer Cells by Utilizing Actively Targetable Folic Acid-Conjugated Albumin Nanospheres. Pharmacological Research, 63, 51-58. http://dx.doi.org/10.1016/j.phrs.2010.10.012
Li, L.L., Yin, Q., Cheng, J.J. and Lu, Y. (2012) Polyvalent Mesoporous Silica Nanoparticle-Aptamer Bioconjugates Target Breast Cancer Cells. Advanced Healthcare Materials, 1, 567-572. http://dx.doi.org/10.1002/adhm.201200116
de la Fuente, J.M. and Penadés, S. (2006) Glyconanoparticles: Types, Synthesis and Applications in Glycoscience, Biomedicine and Material Science. Biochimica et Biophysica Acta, 1760, 636-651.
Veerapandian, M. and Yun, K. (2010) Synthesis of Silver Nanoclusters and Functionalization with Glucosamine for Glyconanoparticles. Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry, 40, 56-64.
Rojo, J., et al. (2004) Gold Glyconanoparticles as New Tools in Antiadhesive Therapy. ChemBioChem, 5, 291-297. http://dx.doi.org/10.1002/cbic.200300726
Mirzaei, M., et al. (2012) Novel Nanosized Gd3+-ALGD-G2-C595: In Vivo Dual Selective MUC-1 Positive Tumor Molecular MR Imaging and Therapeutic Agent. Journal of Nanomedicine Nanotechnology, 3, 1-6. http://dx.doi.org/10.4172/2157-7439.1000147
Mirzaei, M., et al. (2012) Gd3+-Anionic Linear Globular Dendrimer-G2-C595 a Dual Novel Nanoprobe for MR Imaging and Therapeutic Agent: An in Vitro Study. Biomolecular Research & Therapeutics, 1, 103.
Bayly, S.R., Fisher, C.L., Storr, T., Adam, M.J. and Orvig, C. (2004) Carbohydrate Conjugates for Molecular Imaging and Radiotherapy: 99mTc(I) and 186Re(I) Tricarbonyl Complexes of N-(2’-Hydroxybenzyl)-2-amino-2-deoxy-D-glucose. Bioconjugate Chemistry, 15, 923-926. http://dx.doi.org/10.1021/bc0499681
Mehravi, B., et al. (2013) Facile Conjugation of Glucosamine on Gd3+ Based Nanoporous Silica Using Heterobifunctional Crosslinker (ANB-NOS) for Cancer Cell Imaging. International Journal of Nanomedicine, 8, 3383-3394. http://dx.doi.org/10.2147/IJN.S44829
Mehravi, B., et al. (2013) Cellular Uptake and Imaging Studies of Glycosylated Silica Nanoprobe (GSN) in Human Colon Adenocarcinoma (HT 29 Cell Line). International Journal of Nanomedicine, 8, 3209-3216. http://dx.doi.org/10.2147/IJN.S44815
Schibli, R., Dumas, C., et al. (2005) Synthesis and in Vitro Characterization of Organometallic Rhenium and Technetium Glucose Complexes against Glut 1 and Hexokinase. Bioconjugate Chemistry, 16, 105-112. http://dx.doi.org/10.1021/bc049774l
Taylor, R.A., Phelan, P.E., Otanicar, T.P., Adrian, R. and Prasher, R. (2011) Nanofluid Optical Property Characterization: Towards Efficient Direct Absorption Solar Collectors. Nanoscale Research Letters, 6, 225. http://dx.doi.org/10.1186/1556-276X-6-225
Ardestani, M.S. (2010) Potential Opponent for 18FDG: Gd3+-DTPA-DG: A New Synthetic MRI Contrast Agent. Iranian Journal of Radiology, 7, 56.
Mehravi, B., et al. (2014) Breast Cancer Cells Imaging By Targeting Methionine Transporters with Gadolinium-Based Nanoprobe. Molecular Imaging and Biology, 16, 519-528. http://dx.doi.org/10.1007/s11307-014-0718-3
Darvish, M.T., et al. (2013) Gd3+-DTPA-Meglumine-Anionic Linear Globular GI: Novel Nanosized Law Toxic Tumor Molecular MR Imaging Agent. ISRN Pharmaceutics, 2013, Article ID: 378452.
Dabbs, D.M. and Aksay, I.A. (2000) Self-Assembled Ceramics Produced by Complex-Fluid Templation. Annual Review of Physical Chemistry, 51, 601-622. http://dx.doi.org/10.1146/annurev.physchem.51.1.601
Buffat, Ph. and Borel, J.-P. (1976) Size Effect on the Melting Temperature of Gold Particles. Physical Review A, 13, 2287. http://dx.doi.org/10.1103/PhysRevA.13.2287
Carretero, M.I. and Pozo, M. (2009) Clay and Non-Clay Minerals in the Pharmaceutical Industry: Part I. Excipients and Medical Applications. Applied Clay Science, 46, 73-80.
Park, J., Cho, W., Park, H.J., Cha, K.H., Ha, D.C., Choi, Y.W., Lee, H.Y., Cho, S.H. and Hwang, S.J. (2013) Biodistribution of Newly Synthesized PHEA-Based Polymer-Coated SPION in Sprague Dawley Rats as Magnetic Resonance Contrast Agent. International Journal of Nanomedicine, 8, 4077-4089.
Quintana, A., Raczka, E., Piehler, L., Lee, I., Myc, A., Majoros, I., Patri, A.K., Thomas, T., Mule, J. and Baker Jr., J.R. (2002) Design and Function of a Dendrimer-Based Therapeutic Nanodevice Targeted to Tumor Cells through the Folate Receptor. Pharmaceutical Research, 19, 1310-1316. http://dx.doi.org/10.1023/A:1020398624602
Dubey, P.K., Mishra, V., Jain, S., Mahor, S. and Vyas, S.P. (2004) Liposomes Modified with Cyclic RGD Peptide for Tumor Targeting. Journal of Drug Targeting, 12, 257-264. http://dx.doi.org/10.1080/10611860410001728040
Reszka, R.C., Jacobs, A. and Voges, J. (2005) Lipo-some-Mediated Suicide Gene Therapy in Humans. Methods in Enzymology, 391, 200-208. http://dx.doi.org/10.1016/S0076-6879(05)91012-4
ten Hagen, T.L. (2005) Liposomal Cytokines in the Treatment of Infectious Diseases and Cancer. Methods in Enzymology, 391, 125-145. http://dx.doi.org/10.1016/S0076-6879(05)91007-0
Thamake, S.I., Raut, S.L., Gryczynski, Z., Ranjan, A.P. and Vishwanatha, J.K. (2012) Alendronate Coated Poly-Lactic-Co-Glycolic Acid (PLGA) Active Targeting of Metastatic Breast Cancer. Biomaterials, 33, 7164-7173. http://dx.doi.org/10.1016/j.biomaterials.2012.06.026
Dhar, S., Gu, F.X., Langer, R., Farokhzade, O.C. and Lippard, S.J. (2008) Targeted Delivery of Cisplatin to Prostate Cancer Cells by Aptamer Functionalized Pt(IV) Prodrug-PLGA-PET Nanoparticles. Proceedings of the National Academy of Sciences, 105, 17356-17361. http://dx.doi.org/10.1073/pnas.0809154105
Yhee, J.Y., Koo, H., Lee, D.E., Choi, K. and Kwon, I.C. (2011). Multifunctional Chitosan Nanoparticles for Tumor Imaging and Therapy. Advances in Polymer Science, 243, 139-161. http://dx.doi.org/10.1007/12_2011_119
Du, H.L., Cai, X.Q. and Zhai, G.X. (2013) Advances in the Targeting Molecules Modified Chitosan-Based Nanoformu lations. Current Drug Targets, 14, 1034-1052. http://dx.doi.org/10.2174/1389450111314090012
Bergey, E.J., Levy, L., Wang, X.P., Krebs, L.J., Lal, M., Kim, K.S., Pakatchi, S., Liebow, C. and Prasad, P.N. (2002) DC Magnetic Field Induced Magnetocytolysis of Cancer Cells Targeted by LH-RH Magnetic Nanoparticles in Vitro. Biomedical Microdevices, 4, 293-299. http://dx.doi.org/10.1023/A:1020906307053
Nurunnabi, Md., Cho, K.J., Choi, J.S., Huh, Y.M. and Lee, Y.-K. (2010) Targeted Near-IR QDs-Loaded Micelles for Cancer Therapy and Imaging. Biomaterials, 31, 5436-5444. http://dx.doi.org/10.1016/j.biomaterials.2010.03.057
Xiao, Y.L., Hong, H., Javadi, A., Engle, J.W., Xu, W.J., Yang, Y.N., Zhang, Y. and Bamhart, T.E. (2012) Multifunctional Unimolecular Micelles for Cancer-Targeted Drug Delivery and Positron Emission Tomography Imaging. Biomaterials, 33, 3071-3082. http://dx.doi.org/10.1016/j.biomaterials.2011.12.030
Gubin, S.P. (2009) Magnetic Nanoparticles. Wiley-VCH, Weinheim. http://dx.doi.org/10.1002/9783527627561
U.S. Food and Drug Administration (2014) Sunscreen.
Mitchnick, M.A., Fairhurst, D. and Pinnell, S.R. (1999) Microfine Zinc Oxide (Z-Cote) as a Photostable UVA/UVB Sunblock Agent. Journal of the American Academy of Dermatology, 40, 85-90. http://dx.doi.org/10.1016/S0190-9622(99)70532-3