Pulmonary function studies in obese individuals have alerted the pathophysiological changes due to weight gain. However, these changes are not fully explained yet. Objective: To evaluate and analyze the pulmonary function of obese adults in the city of Manaus (AM, Brazil) and to correlate the parameters of spirometry with weight and BMI. Method: A descriptive cross-sectional study, in which pulmonary function of 22 adults with grade III obesity was evaluated pre and post bronchodilator administration, performed at the Adriano Jorge Hospital Foundation—FHAJ. Results: Of the 22 patients evaluated, 6 were male and 16 were female; mean age was 37.1 ± 7.4 years, with a weight of 134.2 ± 28.6 kg and a BMI of 51.1 ± 9.4 kg/m 2 , corresponding to grade III obesity. Spirometry showed a reduction in values obtained from Forced Vital Capacity (FVC), Forced Expiratory Volume in the first second (FEV1) and Peak Expiratory Flow (PEF) in relation to those predicted, with 23% of restrictive disorders. There were negative correlations between BMI and PEF, weight and FVC, weight and PEF. The P value for correlation of weight and FEV1 is not statistically significant. Conclusion: Restrictive and obstructive disorders are prevalent in the population with grade III obesity. Correlations between pulmonary function and BMI/weight were negative for this specific population.
World Health Organization (1998) Obesity: Preventing and Managing the Global Epidemic—Report of a WHO Consultation on Obesity. Report, World Health Organization, Geneva.
Marcelino, L.F. and Patrício, Z.M. (2011) The Complexity of Obesity and the Process of Living after Bariatric Surgery: A Collective Health Issue. Science & Collective Health, 16, 4767-4776.
Fontaine, K.R. and Barofsky, I. (2001) Obesity and Health-Related Quality of Life. Obesity Research, 3, 173-182. https://doi.org/10.1046/j.1467-789x.2001.00032.x
World Health Organization (2016) Obesity and Overweight. http://www.who.int/mediacentre/factsheets/fs311/en/
INAN (1991) Nutritional Conditions of the Brazilian Population: Adults and the Elderly. National Research on Health and Nutrition. National Institute of Food and Nutrition, Ministry of Health, Brasília.
Wanderley, E.M. and Ferreira, V.A. (2010) Obesity: A Plural Perspective. Ciencia & Saúde Coletiva, 15, 185-194. https://doi.org/10.1590/S1413-81232010000100024
Gontijo, P.L., Lima, T.P., Costa, T.R., Reis, E.P., Cardoso, F.P.F. and Neto, F.F.C. (2011) Correlation of Spirometry with the Six-Minute Walk Test in Eutrophic and Obese Patients. Revista Da Associacao Medica Brasileira, 57, 387-393. https://doi.org/10.1590/S0104-42302011000400010
Carvalho, E.A.A., Simao, M.T.J., Fonseca, M.C., et al. (2013) Obesity: Epidemiological Aspects and Prevention. Revista Da Associacao Medica Brasileira, , 23 , 74-82.
Marques-Lopes, I., Marti, A., Moreno-Aliaga, M.J. and Martinez, A. (2004) Aspectos Gênicos da Obesidade. Nutrition Reviews, 17, 327-338. https://doi.org/10.1590/S1415-52732004000300006
Pereira, L.O., Francischi, R.P. and Lancha, J.R. (2003) Obesity: Nutritional Habits, Sedentary Lifestyle and Insulin Resistance. Brazilian Archives of Metabolic Endocrinology, 47, 111-127.
Rey-Lopez, J.P., de Rezende, L.F., de Sá, T.H. and Stamatakis, E. (2015) Is the Metabolically Healthy Obesity Phenotype an Irrelevant Artifact for Public Health? American Journal of Epidemiology, 182, 737-741. https://doi.org/10.1093/aje/kwv177
Ribeiro, G.F., Araújo, L.M.B., Souza-Machado, A. and Ribeiro, P.A. (2007) Evaluation of Pulmonary Function in Obese Asymptomatic Respiratory Subjects: Correlation between Anthropometric and Spirometric Data. Revista Brasileira de Alergia e Imunopatologia, 30, 227-231.
Wang, S., Sun, X., Hsia, T-C., Lin, X. and Li, M. (2017) The Effects of Body Mass Index on Spirometry Tests among Adults in Xi’an, China. Medicine, 96, e6596. https://doi.org/10.1097/MD.0000000000006596.
Melo, L.C., da Silva, M.A.M. and do Nascimento Calles, A.C. (2014) Obesity and Pulmonary Function: A Systematic Review. Einstein, 12, 120-125.
Rasslan, Z., Stirbulov, R., Lima, C.A.C. and Junior, R.S. (2009) Pulmonary Function and Obesity. Revista Brasileira de Clínica Médica, 7, 36-39.
Stirbulov, R. (2007) Respiratory Repercussions of Obesity. Brasileiro de Pneumologia, 33, 7-8.
American Thoracic Society/European Respiratory Society (2002) ATS/ERS Statement on Respiratory Muscle Testing. American Journal of Respiratory and Critical Care Medicine, 166, 518-624. https://doi.org/10.1164/rccm.166.4.518
Brazilian Society of Pulmonology and Tisiology (2002) Guidelines for Lung Function Tests. Jornal Brasileiro de Pneumologia, 28, S1-S238.
Global Initiative for Chronic Obstructive Lung Disease (2015) Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease. http://www.goldcopd.org
Bedell, G.N., Wilson, W.R. and Seebohm, P.M. (1958) Pulmonary Function in Obese Person. Journal of Clinical Investigation, 37, 1049-1060. https://doi.org/10.1172/JCI103686
Lean, M.E., Han, T.S. and Morrison, C.E. (1995) Waist Circumference as a Measure for Indicating Need for Weight Management. British Medical Journal, 311,158-161. https://doi.org/10.1136/bmj.311.6998.158
Sahebjami, H. (1998) Dyspnea in Obese Healthy Men. Chest, 114, 1373-1377. https://doi.org/10.1378/chest.114.5.1373
Rasslan, Z., Saad Junior, R., Stirbulov, R., Fabbri, R.M.A. and Lima, C.A.C. (2004) Evaluation of Lung Function in Obesity Grades I and II. Brazilian Journal of Pulmonology, 30, 508-514.
Collins, C.L., Hoberty, P.D., Walker, J.F., Fletcher, E.C. and Peiris, A.N. (1995) The Effects of Body Fat Distribution on Pulmonary Function Tests. Chest, 107, 1298-1302. https://doi.org/10.1378/chest.107.5.1298
Jones, R.L. and Nzekwu, M.U. (2006) The effects of Body Mass Index on Lung Volumes. Chest, 130, 827-833. https://doi.org/10.1378/chest.130.3.827
Melo, S.A.D., de Melo, V.A., Menezes Filho, R.S. and Santos, F.A. (2011) Efeitos do aumento progressivo do peso corporal na funcao pulmonar em seis grupos de índice de massa corpórea. Revista da Associacao Médica Brasileira, 57, 509-515. https://doi.org/10.1590/S0104-42302011000500007
Domingos-Benicio, N.C., Gastaldi, A.C., Perecin, J.C, Avena, K.M., Guimaraes, R.C., Sologuren, M.J.J., et al. (2004) Spirometric Measurements in Obese People in Orthostatic, Sitting and Lying Positions. Revista da Associacao Médica Brasileira, 50, 142-147.
Hari-Klan, R.I., Fleg, J.L. and Wise, R.A. (2001) The Effect of Gender of the Relationship between Body Fat Distribution and Lung Function. Journal of Clinical Epidemiology, 54, 339-406.
Hintze, L.J., Bevilaqua, C.A., Pimentel, E.B. and Nardo-Junior, N. (2011) Bariatric Surgery in Brazil. Revista Ciências Médicas, 20, 87-98.
De Oliveira, P.D., Wehrmeister, F.C., Pérez-Padilla, R., Goncalves, H., Assuncao, M.C.F., Horta, B.L., et al. (2016) Relationship between Body Composition and Pulmonary Function in Early Adult Life: A Cross-Sectional Analysis Nested in Two Birth Cohort Studies. Public Library of Science, 11.
Al Ghobain, M. (2012) The Effect of Obesity on Spirometry Tests among Healthy Non-Smoking Adults. BMC Pulmonary Medicine, 12, 10. https://doi.org/10.1186/1471-2466-12-10