Florid Autonomic Features Associated with Medullary Lacunar Stroke
- 1 Department of Neurology, Al Qassemi Hospital (EHS) Emirates Health Services, Sharjah, UAE
- 2 Faculty of Medicine and Health Sciences, Omdurman Islamic University, Omdurman, Sudan
- 3 Faculty of Medicine and Health Sciences, Omdurman Islamic University, Omdurman, Sudan
- 4 Department of Neurology, Al Qassemi Hospital (EHS) Emirates Health Services, Sharjah, UAE
- 5 Department of Neurology, Al Qassemi Hospital (EHS) Emirates Health Services, Sharjah, UAE
- 6 Department of Neurology, Al Qassemi Hospital (EHS) Emirates Health Services, Sharjah, UAE
- 7 Department of Neurology, Al Qassemi Hospital (EHS) Emirates Health Services, Sharjah, UAE
Abstract
Introduction: Autonomic nuclei affection results in variations in hemodynamics, temperature, sweating and ECG. Medullary strokes are challenging in their presentation, bizarre clinical signs, work and neurological outcome. The commonest cause is infarction of the posterior inferior cerebellar artery (PICA). Anatomical areas affected include the inferior cerebellar peduncle, dorsolateral medulla, nuclei of the Trigeminal, vestibular nuclei, Ninth and Vagus nerves. The descending sympathetic tracts and spin thalamic tracts. Serious cardiopulmonary events can complicate 11% of cases. Case Presentation: A middle-aged female developed sub-acute dizziness associated with vomiting and right head pains. She was unable to walk but remained cognitively clear. Her gastrointestinal symptoms were disabling and this was the main factor for presenting to the emergency room. The risk factors included hypertension and diabetes mellitus. Imaging studies were essential for posterior circulation stroke diagnosis and follow-up. She manifested remarkable autonomic features regarding the skin and hemodynamics. Nevertheless, the hospital course was controllable. Discussion: This case report was consistent with relevant literature in the contra lateral vaso motor changes and drop in body temperature during the acute phase. Moreover, our patient developed clinical and radiological extension through double antiplatelets. Superiority of the magnetic resonance imaging (MRI) scans in this patient enabled better diagnostic accuracy in a brainstem stroke. Conclusion: The autonomic features, in this case, represent major symptomatology and clinical signs. The variation in the hemodynamics and persistence of symptoms is thought provoking. This increases the awareness of emergency doctors for acute stroke presenting with autonomic features will enable early detection and helps outcome.
- Sawada, H., Seriu, N., Udaka, F. and Kameyama, M. (1992) Autonomic Dysfunction of Central Nervous System Disorders. Nihon Rinsho Japanese Journal of Clinical Medicine, 50, 799-805.
- Scott-Solomon, E., Boehm, E. and Kuruvilla, R. (2021) The Sympathetic Nervous System in Development and Disease. Nature Reviews Neuroscience, 22, 685-702. https://doi.org/10.1038/s41583-021-00523-y
- Tao, L.S., Lin, J.J., Zou, M., et al. (2021) A Comparative Analysis of 375 Patients with Lateral and Medial Medullary Infarction. Brain and Behavior, 11, e2224. https://doi.org/10.1002/brb3.2224
- Kim, H., Lee, H.J., Park, J.W. et al. (2018) Clinical Course and Outcome in Patients with Severe Dysphagia after Lateral Medullary Syndrome. Therapeutic Advances in Neurological Disorders, 11, 1-6. https://doi.org/10.1177/1756286418759864
- Gasca-Gonzalez, O.O., Perez-Cruz, J.C., Baldoncini, M., et al. (2020) Neuroanatomical Basis of Wallenberg Syndrome. Cirugia y Cirujanos, 88, 376-382. https://doi.org/10.24875/CIRU.19000801
- Day, G.S., Swartz, R.H., Chenkin, J., et al. (2014) Lateral Medullary Syndrome: A Diagnostic Approach Illustrated through Case Presentation and Literature Review. Cjem, 16, 164-170. https://doi.org/10.2310/8000.2013.131059
- Vallis-Sole, J., Vila, N., Obach, V., Alvarez, R., et al. (1996) Brain Stem Reflexes in Patients with Wallenberg’s Syndrome: Correlation with Clinical and Magnetic Resonance Imaging (MRI) Findings. Muscle & Nerve, 19, 1093-1099. https://doi.org/10.1002/(SICI)1097-4598(199609)19:9 3.0.CO;2-V
- Norrving, B. and Cronqvist, S. (1991) Lateral Medullary Infarction: Prognosis in an Unselected Series. Neurology, 41, 244-248. https://doi.org/10.1212/WNL.41.2_Part_1.244
- Perez de Llano, L.A., Pego Reigosa, R. and Branas Fernandez, F. (1999) Comment on “Respiratory Failure Secondary to Disautonomy in Lateral Bulbar Infarction”. Neurologia, 14, 94-95.
- Kuwabara, S. and Hirayama, K. (1995) Headache in Lateral Medullary Infarction. Journal of Neurology, Neurosurgery, and Psychiatry, 59, 341. https://doi.org/10.1136/jnnp.59.3.341
- Korpelainen, J.T., Sotaniemi, K.A. and Myllyla, V.V. (1995) Asymmetrical Skin Temperature in Ischemic Stroke. Stroke, 26, 1543-1547. https://doi.org/10.1161/01.STR.26.9.1543
- Nakazato, Y., Shimazu, K., Tamura, N., et al. (1995) A Study of Skin Surface Temperature in Patients with Unilateral Cerebral Infarction—With Special Reference to Central Autonomic Regulation of Skin Vasomotor Response. Rinsho Shinkeigaku (Clinical Neurology), 35, 758-763.