Background and Objective: Unwanted hair growth is a discomforting issue affecting both genders. People have tried various methods to get rid of this situation. This study aims to evaluate the efficacy and safety of a combined Alexandrite and Nd:YAG laser treatment for permanent hair removal, drawing insights from existing literature. Materials and Methods: This study included a total of 2127 patients (302 males, 1825 females) aged 18 - 65, with complete data, who underwent hair removal treatment between December 2018 and April 2021. These patients were treated using the Duetta laser system (Quanta system, Samarate, Italy), combining Alexandrite 755 nm and Nd:YAG 1064 nm wavelengths. The patients’ skin types were classified according to the Fitzpatrick classification scale. Target area/areas for laser hair removal was/were determined. Laser parameters, pulse counts, pain levels assessed through the Visual Pain Scale (VPS), and patient satisfaction were documented based on skin types. Findings: Across various skin types, Types I - II exhibited the highest treatment success rates (87%), with the axillary region achieving the highest rate (83%) and the face region achieving the lowest rate (75%). Pain scale analysis indicated that 98% of patients tolerated the procedure well. Patient satisfaction levels exceeded 90%. Evaluation of complication rates revealed minimal occurrences. Conclusion: The combined Alexandrite and Nd:YAG laser system demonstrates both efficacy and safety across diverse skin types, attributed to its notable success rates, minimal adverse effects, and high patient tolerance.
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