Practical Enlightenment from the Application of Central Venous Catheters in Neoadjuvant Chemotherapy for Osteosarcoma Patients

Abstract

Objective: Analyze the effects of central venous catheterization during neoadjuvant chemotherapy in osteosarcoma patients to derive enlightenment. Methods: Eighty osteosarcoma patients who received neoadjuvant chemotherapy in our hospital from January 2023 to December 2024 were selected as the observation objects. All these 80 osteosarcoma patients had central venous catheters (including PICC catheters and venous port catheters). Nursing care was provided to these patients, and practical insights were obtained through analysis. Results: Among the 80 osteosarcoma patients who underwent central venous catheterization, there was one case where the catheter was removed due to blockage, which caused poor fluid infusion and no blood return upon aspiration. Three patients had their catheters removed upon completion of the treatment course as per the doctor’s orders. The remaining 76 patients continued to use their catheters, and regular maintenance and nursing care were promptly provided throughout the process. Conclusion: During the neoadjuvant chemotherapy for osteosarcoma patients, the use of central venous catheters can not only avoid the damage caused by repeated peripheral venous punctures, establish a good pathway for subsequent nutritional support, reduce the damage of chemotherapy drugs to peripheral blood vessels and the risk of drug extravasation, but also meet the intensive administration requirements of osteosarcoma neoadjuvant chemotherapy regimens. It is suitable for pediatric and adolescent osteosarcoma patients, bringing convenience to the treatment of osteosarcoma patients.