The Murmur of Dynamic Subortic Stenosis Recognition Through A Novel Graphic Display
- 1 St. Vincent Hospital, Indiana University School of Medicine, Indianapolis, USA
Abstract
Background: Dynamic subaortic stenosis occurs in differing situations, commonly with hypertrophic cardiomyopathy. Regardless of the underlying cause, the resulting murmurs usually possess a characteristic sound spectral pattern, manifesting a sharp and high frequency peak occurring late in systole, often bearing a striking resemblance to the subaortic Doppler flow pattern. Methods: Murmurs found in thirty one subjects with dynamic subaortic stenosis were analyzed after having been recorded with a novel portable device capable of spectral and waveform sound displays. Results: All subjects manifested characteristic frequency patterns, consisting of high and sharp peaks occurring in late systole. With significant subaortic stenosis (resting subaortic flow velocity > 2 m/sec) this pattern was evident at rest. In the presence of little or no resting subaortic obstruction (< 2 m/sec) this pattern was produced regularly by the Valsalva maneuver. Conclusions: Dynamic subaortic stenosis produces a specific sound spectral pattern that may provide a basis for clinical evaluation, especially in early detection of this disorder and in screening situations.
- Maron BJ, Maron MS, Wigle D, et al. The 50-year history, controversy, and clinical implications of left ventricular outflow tract obstruction in hypertrophic cardiomyopathy. J. Am. Coll Cardiol 2009;54:191-200.
- Tavel ME. Clinical Phonocar-diography and External Pulse Recording. Year Book Medical Publishers (4th Ed), Chicago, Ill, 1985, p. 147.
- Spooner PH, Perry P, Brandenburg RO, and Pennock GD. Increased intraventricular velocities: An unrecognized cause of systolic murmur in adults. J. Am. Coll Cardiol 1998;32:1589-95.
- Lever HM, Karam RF, Currie PJ, et al. Hypertrophic cardiomyopathy in the elderly. Circulation 1989;79:580-589.
- Harrison MR, Grigsby CG, Southern SK, Smith MD, et al. Midventricular obstruction associated with chronic systemic hypertension and severe left ventricular hypertrophy. Am J Cardiol 1991;68:761-765.
- Minami Y, Kajimoto K, Terajima Y, Yashiro B, Okayama D, Haruki S, Nakajima T, Kawashiro N, Kawana M, and Hagiwara N. Cli nical implications of midventricular obstruction in patients with hypertrophic cardiomyopathy. J. Am. Col. Cardiol. 2011;57:2346-2355.
- Fukuda N, Oki T, Iuchi A, Tabata T, Manabe K, et al. Clinical significance of the apical late systolic ejection murmur: A new phonocardiographic sign indicating dynamic mid-left ventricular obstruction. Clin. Cardiol. 1996;19:121-127.
- Armstrong WF, and Ryan T: Feigen-baum’s Echocardiography (6th Ed.) Lippincott Williams and Wilkins, Philadelphia, 2005. p. 549
- Tavel ME and Katz H: Usefulness of a new sound spectral averaging technique to distinguish an innocent systolic murmur from that of aortic stenosis. Am J Cardiol. 2005;95:902-904
- Armstrong WF, and Ryan T: Feigenbaum’s Echocardiography (6th Ed.) Lippin-cott Williams and Wilkins, Philadelphia, 2005. p. 545.
- Kim D and Tavel ME: Assessment of severity of aortic stenosis through time-frequency analysis of murmur. Chest 2003;124:1638-1644.
- Tavel ME. Cardiac ausculta-tion: A glorious past—and it does have a future! Circulation 2006;113:1255-1259.
- Maron MS, Olivotto I, Zenovich AG, et al. Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction. Circulation. 2006;114:2323-2239.
- Tavel ME and Bates: The cervical bruit: sound spectral analysis related to severity of carotid arterial disease. Clin. Cardiol. 2006;29:462-465.