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Sporadic Creutzfeldt-Jakob Disease Presenting with Visual Disturbance—A Case Report in China
Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China;
Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
- 1 Department of Ophthalmology, Eye and ENT Hospital, Fudan University, Shanghai, China;
- 2 Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
- 3 Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
- 4 Department of Neurology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
International Journal of Clinical Medicine·Volume 04 (2013)·Pages 321–324·Published 4 July 2013·DOI10.4236/ijcm.2013.47057
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Abstract
Creutzfeldt-Jakob disease (CJD) is a rare but fatal neurodegenerative prion disease. Classic CJD comprises a clinical triad of rapidly progressive dementia, myoclonus, and EEG abnormality. At initial presentation, this classic triad is present only in a minority of cases. Visual impairment is one of the predominant manifestations in the course of CJD, especially in Heidenhain variant phenotype. We reported a case presenting with progressive blurred vision, along with other neurological symptoms, who diagnosed as sporadic CJD with cortical blindness in China.
KeywordsCreutzfeldt-Jakob DiseaseVisual DisturbanceHeidenhain VariantDiffusion Weighted Imaging
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