Helicopter Emergency Medical Services (HEMS) use in civilian medical transport has its roots in the use of rotor-wing trauma transport in the military setting. Much of the literature and evidence based on the use of HEMS is therefore re lated to scene and interfacility transport of injured patients. Regionalization of care and increased understanding of time- criticality of various non - trauma conditions has contributed to growing utilization of HEMS for non - trauma conditions over recent decades. It is common for HEMS to be utilized for a variety of non - trauma situations ranging from neonatal and obstetrics transports to cardiac and stroke transports. The purpose of this review is to overview the use of HEMS for non - trauma, focusing on situations in which there is evidence addressing possible HEMS utility.
KeywordsHelicopter Emergency Medical ServicesAir Medical TransportPrehospital Care
C. Moga and C. Harstall, “Air Ambulance Transportation with Capabilities to Provide Advanced Life Support: IHE Report to the Ministry of Health,” Institute of Health Economics, Calgary, 2007.
S. M. Galvagno Jr., S. Thomas, C. Stephens, E. R. Haut, J. M. Hirshon, D. Floccare and P. Pronovost, “Helicopter Emergency Medical Services for Adults with Major Trauma,” Cochrane Database of Systematic Reviews, Vol. 3, 2013, Article ID: CD009228.
D.P. Thomson, S.H. Thomas, “Guidelines for air medical dispatch,” Prehospital Emergency Care, Vol. 7, No. 2, 2003, pp. 265-271. http://dx.doi.org/10.1080/10903120390936923
J. Varon, R. Fromm and P. Marik, “Hearts in the Air,” Chest, Vol. 124, No. 5, 2003, pp. 1636-1637. http://dx.doi.org/10.1378/chest.124.5.1636
R. Kent, L. Newman, R. Johnson and R. Carraway, “Helicopter Transport of Ruptured Abdominal Aortic Aneurysms,” Ala Med, Vol. 58, 1989, pp. 13-14.
J. Bruhn, K. Williams and R. Aghababian, “True Costs of Air Medical vs. Ground Ambulance Systems,” Air Medical Journal, Vol. 12, No. 8, 1993, pp. 262-268. http://dx.doi.org/10.1016/S1067-991X(05)80311-6
D. P. Davis, J. Peay, B. Good, M. J. Sise, F. Kennedy, A. B. Eastman, T. Velky and D. B. Hoyt, “Air Medical Response to Traumatic Brain Injury: A Computer Learning Algorithm Analysis,” Journal of Trauma, Vol. 64, No. 4, 2008, pp. 889-897. http://dx.doi.org/10.1097/TA.0b013e318148569a
S. H. Thomas, L. H. Schwamm and M. H. Lev, “Case Records of the Massachusetts General Hospital. Case 16-2006. A 72-Year-Old Woman Admitted to the Emergency Department Because of a Sudden Change in Mental Status,” New England Journal of Medicine, Vol. 354, No. 21, 2006, pp. 2263-2271. http://dx.doi.org/10.1056/NEJMcpc069007
N. Hata, N. Kobayashi, T. Imaizumi, S. Yokoyama, T. Shinada, J. Tanabe, K. Shiiba, Y. Suzuki, H. Matsumoto and K. Mashiko, “Use of an Air Ambulance System Improves Time to Treatment of Patients with Acute Myocardial Infarction,” Internal Medicine, Vol. 45, No. 2, 2006, pp. 45-50. http://dx.doi.org/10.2169/internalmedicine.45.1399
T. Imaizumi, N. Hata, N. Kobayashi, S. Yokoyama, T. Shinada, K. Tokuyama, M. Ishikawa, K. Shiiba, H. Matsumoto, K. Takuhiro and K. Mashiko, “Early Access to Patients with Life-Threatening Cardiovascular Disease by an Air Ambulance Service,” Journal of Nippon Medical School, Vol. 71, No. 5, 2004, pp. 352-356. http://dx.doi.org/10.1272/jnms.71.352
C. Palmer, J. McMullan, W. Knight, M. Gunderman and W. Hinckley, “Helicopter Scene Response for a STEMI Patient Transported Directly to the Cardiac Catheterization Laboratory,” Air Medical Journal, Vol. 30, No. 6, 2011, pp. 289-292. http://dx.doi.org/10.1016/j.amj.2011.08.005
S. H. Thomas and A. Arthur, “Helicopter EMS: Research Endpoints and Potential Benefits,” EM International, 2012.
D. J. Floccare, D. F. Stuhlmiller, S. A. Braithwaite, S. H. Thomas, J. F. Madden, D. G. Hankins, H. Dhindsa and M. G. Millin, “Appropriate and Safe Utilization of Helicopter Emergency Medical Services: A Joint Position Statement with Resource Document,” Prehospital Emergency Care, Vol. 17, No. 4, 2013, pp. 521-525. http://dx.doi.org/10.3109/10903127.2013.804139
I. Blumen, “A Safety Review and Risk Assessment in Air Medical Transport,” Air Medical Physician Association, Salt Lake City, 2002.
K. S. Berns, D. G. Hankins and S. P. Zietlow, “Comparison of Air and Ground Transport of Cardiac Patients,” Air Medical Journal, Vol. 20, No. 6, 2001, pp. 33-36. http://dx.doi.org/10.1016/S1067-991X(01)70008-9
M. Phillips, A. O. Arthur, R. Chandwaney, J. Hatfield, B. Brown, K. Pogue, M. Thomas, M. Lawrence, M. McCarroll, M. McDavid and S. H. Thomas, “Helicopter Transport Effectiveness of Patients for Primary Percutaneous Coronary Intervention,” Air Medical Journal, Vol. 32, No. 3, 2013, pp. 144-152. http://dx.doi.org/10.1016/j.amj.2012.08.007
B. K. Nallamothu, E. H. Bradley and H. M. Krumholz, “Time to Treatment in Primary Percutaneous Coronary Intervention,” New England Journal of Medicine, Vol. 357, 2007, pp. 1631-1638. http://dx.doi.org/10.1056/NEJMra065985
J. L. Saver, G. C. Fonarow, E. E. Smith, M. J. Reeves, M. V. Grau-Sepulveda, W. Pan, D. M. Olson, A. F. Hernandez, E. D. Peterson and L. H. Schwamm, “Time to Treatment with Intravenous Tissue Plasminogen Activator and Outcome from Acute Ischemic Stroke,” JAMA, Vol. 309, No. 23, 2013, pp. 2480-2488. http://dx.doi.org/10.1001/jama.2013.6959
W. M. Konstantopoulos, J. Pliakas, C. Hong, K. Chan, G. Kim, L. Nentwich and S. H. Thomas, “Helicopter Emergency Medical Services and Stroke Care Regionalization: Measuring Performance in a Maturing System,” American Journal of Emergency Medicine, Vol. 25, No. 2, 2007, pp. 158-163. http://dx.doi.org/10.1016/j.ajem.2006.06.016
S. H. Thomas, C. Kociszewski, R. J. Hyde, P. J. Brennan and S. K. Wedel, “Prehospital Electrocardiogram and Early Helicopter Dispatch to Expedite Interfacility Transfer for Percutaneous Coronary Intervention,” Critical Pathways in Cardiology, Vol. 5, No. 3, 2006, pp. 155-159. http://dx.doi.org/10.1097/01.hpc.0000234809.93495.e3
Z. J. Rhinehart, F. X. Guyette, J. L. Sperry, R. M. Forsythe, A. Murdock, L. H. Alarcon, A. B. Peitzman and M. R. Rosengart, “The Association between Air Ambulance Distribution and Trauma Mortality,” Annals of Surgery, Vol. 257, No. 6, 2013, pp. 1147-1153. http://dx.doi.org/10.1097/SLA.0b013e31827ee6b0
E. Straumann, S. Yoon and B. Naegeli, “Hospital Transfer for Primary Coronary Angioplasty in High Risk Patients with Acute Myocardial Infarction,” Heart, Vol. 82, 1999, pp. 415-419.
J. Elliott, D. O’Keeffe and R. Freeman, “Helicopter Transportation of Patients with Obstetric Emergencies in an Urban Area,” American Journal of Obstetrics & Gynecology, Vol. 143, 1982, pp. 157-162.
S. Berge, C. Berg-Utby and E. Skogvoll, “Helicopter Transport of Sick Neonates: A 14-Year Population-Based Study,” Acta Anaesthesiologica Scandinavica, Vol. 49, No. 7, 2005, pp. 999-1003. http://dx.doi.org/10.1111/j.1399-6576.2005.00712.x
A. Tyson, D. Sundberg, D. Sayers, K. Ober and R. Snow, “Plasma Catecholamine Levels in Patients Transported by Helicopter for Acute Myocardial Infarction and Unstable Angina Pectoris,” American Journal of Emergency Medicine, Vol. 6, No. 5, 1988, pp. 435-438. http://dx.doi.org/10.1016/0735-6757(88)90240-9
R. Fromm, D. Taylor, L. Cronin, W. McCallum and R. Levine, “The Incidence of Pacemaker Dysfunction during Helicopter Air Medical Transport,” American Journal of Emergency Medicine, Vol. 10, No. 4, 1992, pp. 333-335. http://dx.doi.org/10.1016/0735-6757(92)90014-O
R. Fromm, E. Hoskins and L. Cronin, “Bleeding Complications Following Initiation of Thrombolytic Therapy for Acute Myocardial Infarction: A Comparison of Helicopter-Transported and Nontransported Patients,” Annals of Emergency Medicine, Vol. 20, No. 8, 1991, pp. 892-895. http://dx.doi.org/10.1016/S0196-0644(05)81433-7
M. R. Le May, D. Y. So, R. Dionne, C. A. Glover, M. P. Froeschl, G. A. Wells, R. F. Davies, H. L. Sherrard, J. Maloney, J. F. Marquis, E. R. O’Brien, J. Trickett, P. Poirier, S. C. Ryan, A. Ha, P. G. Joseph and M. Labinaz, “A Citywide Protocol for Primary PCI in ST-Segment Elevation Myocardial Infarction,” New England Journal of Medicine, Vol. 358, No. 3, 2008, pp. 231-240. http://dx.doi.org/10.1056/NEJMoa073102
E. Keeley and L. Hills, “Clinical Therapeutics: Primary PCI for Myocardial Infarction with ST-Segment Elevation,” New England Journal of Medicine, Vol. 356, No. 1, 2007, pp. 47-52. http://dx.doi.org/10.1056/NEJMct063503
C. Grines, D. Westerhausen and L. Grines, “A Randomized Trial of Transfer for Primary Angioplasty versus On-Site Thrombolysis in Patients with High-Risk Myocardial Infarction (Air PAMI Trial),” Journal of the American College of Cardiology, Vol. 39, No. 11, 2002, pp. 1713-1719. http://dx.doi.org/10.1016/S0735-1097(02)01870-3
D. B. Diercks, M. C. Kontos, J. E. Weber and E. A. Amsterdam, “Management of ST-Segment Elevation Myocardial Infarction in EDs,” American Journal of Emergency Medicine, Vol. 26, No. 1, 2008, pp. 91-100. http://dx.doi.org/10.1016/j.ajem.2007.06.014
S. S. Rathore, J. P. Curtis, J. Chen, Y. Wang, B. K. Nallamothu, A. J. Epstein and H. M. Krumholz, “Association of Door-to-Balloon Time and Mortality in Patients Admitted to Hospital with ST Elevation Myocardial Infarction: National Cohort Study,” BMJ, Vol. 338, 2009, p. b1807.
D. S. Pinto, A. J. Kirtane, B. K. Nallamothu, S. A. Murphy, D. J. Cohen, R. J. Laham, D. E. Cutlip, E. R. Bates, P. D. Frederick, D. P. Miller, J. P. Carrozza Jr., E. M. Antman, C. P. Cannon and C. M. Gibson, “Hospital Delays in Reperfusion for ST-Elevation Myocardial Infarction: Implications When Selecting a Reperfusion Strategy,” Circulation, Vol. 114, No. 19, 2006, pp. 2019-2025. http://dx.doi.org/10.1161/CIRCULATIONAHA.106.638353
J. B. Myers, C. M. Slovis, M. Eckstein, J. M. Goodloe, S. M. Isaacs, J. R. Loflin, C. C. Mechem, N. J. Richmond and P. E. Pepe, “Evidence-Based Performance Measures for Emergency Medical Services Systems: A Model for Expanded EMS Benchmarking,” Prehospital Emergency Care, Vol. 12, No. 2, 2008, pp. 141-151. http://dx.doi.org/10.1080/10903120801903793
G. De Luca, G. Biondi-Zoccai and P. Marino, “Transferring Patients with ST-Segment Elevation Myocardial Infarction for Mechanical Reperfusion: A Meta-Regression Analysis of Randomized Trials,” Annals of Emergency Medicine, Vol. 52, No. 6, 2008, pp. 665-676. http://dx.doi.org/10.1016/j.annemergmed.2008.08.033
J. C. Blankenship, T. A. Haldis, G. C. Wood, K. A. Skelding, T. Scott and F. J. Menapace, “Rapid Triage and Transport of Patients with ST-Elevation Myocardial Infarction for Percutaneous Coronary Intervention in a Rural Health System,” American Journal of Cardiology, Vol. 100, No. 6, 2007, pp. 944-948. http://dx.doi.org/10.1016/j.amjcard.2007.04.031
A. P. Reimer, F. M. Hustey and D. Kralovic, “Decreasing Door-to-Balloon Times via a Streamlined Referral Protocol for Patients Requiring Transport,” American Journal of Emergency Medicine, Vol. 31, No. 3, 2013, pp. 499-503. http://dx.doi.org/10.1016/j.ajem.2012.09.031
S. Cheskes, L. Turner, R. Foggett, M. Huiskamp, D. Popov, S. Thomson, G. Sage, R. Watson and R. Verbeek, “Paramedic Contact to Balloon in Less than 90 Minutes: A Successful Strategy for ST-Segment Elevation Myocardial Infarction Bypass to Primary Percutaneous Coronary Intervention in a Canadian Emergency Medical System,” Prehospital Emergency Care, Vol. 15, No. 4, 2011, pp. 490-498.
J. T. McMullan, W. Hinckley, J. Bentley, T. Davis, G. J. Fermann, M. Gunderman, K. W. Hart, W. A. Knight, C. J. Lindsell, C. Miller, A. Shackleford and W. Brian Gibler, “Ground Emergency Medical Services Requests for Helicopter Transfer of ST-Segment Elevation Myocardial Infarction Patients Decrease Medical Contact to Balloon Times in Rural and Suburban Settings,” Academic Emergency Medicine, Vol. 19, No. 2, 2012, pp. 153-160. http://dx.doi.org/10.1111/j.1553-2712.2011.01273.x
T. W. Concannon, D. M. Kent, S. L. Normand, J. P. Newhouse, J. L. Griffith, J. Cohen, J. R. Beshansky, J. B. Wong, T. Aversano and H. P. Selker, “Comparative Effectiveness of ST-Segment-Elevation Myocardial Infarction Regionalization Strategies,” Circulation: Cardiovascular Quality and Outcomes, Vol. 3, 2010, pp. 506-513. http://dx.doi.org/10.1161/CIRCOUTCOMES.109.908541
L. F. Peterson and L. R. Peterson, “The Safety of Performing Diagnostic Cardiac Catheterizations in a Mobile Catheterization Laboratory at Primary Care Hospitals,” Angiology, Vol. 55, No. 5, 2004, pp. 499-506. http://dx.doi.org/10.1177/000331970405500505
A. D. Frutkin, S. K. Mehta, T. Patel, P. Menon, D. M. Safley, J. House, C. W. Barth Ⅲ, J. A. Grantham and S. P. Marso, “Outcomes of 1,090 Consecutive, Elective, Nonselected Percutaneous Coronary Interventions at a Community Hospital without Onsite Cardiac Surgery,” American Journal of Cardiology, Vol. 101, No. 1, 2008, pp. 53-57. http://dx.doi.org/10.1016/j.amjcard.2007.07.047
W. J. Cantor, D. Fitchett, B. Borgundvaag, J. Ducas, M. Heffernan, E. A. Cohen, L. J. Morrison, A. Langer, V. Dzavik, S. R. Mehta, C. Lazzam, B. Schwartz, A. Casanova, S. G. Goodman and T.-A.T. Investigators, “Routine Early Angioplasty after Fibrinolysis for Acute Myocardial Infarction,” The New England Journal of Medicine, Vol. 360, No. 26, 2009, pp. 2705-2718. http://dx.doi.org/10.1056/NEJMoa0808276
G. Lindbeck, D. Groopman and R. Powers, “Aeromedical Evacuation of Rural Victims of Nontraumatic Cardiac Arrest,” Annals of Emergency Medicine, Vol. 22, No. 8, 1993, pp. 1258-1262. http://dx.doi.org/10.1016/S0196-0644(05)80103-9
H. Werman, R. Falcone, S. Shaner, H. Herron, R. Johnson, P. Lacey, S. Childress and G. Kampman “Helicopter Transport of Patients to Tertiary Care Centers after Cardiac Arrest,” The American Journal of Emergency Medicine, Vol. 17, No. 2, 1999, pp. 130-134. http://dx.doi.org/10.1016/S0735-6757(99)90043-8
J. L. Saver, “Time Is Brain--Quantified,” Stroke, Vol. 37, No. 1, 2006, pp. 263-266. http://dx.doi.org/10.1161/01.STR.0000196957.55928.ab
J. A. Chalela, S. E. Kasner, E. C. Jauch and A. M. Pancioli, “Safety of Air Medical Transportation after Tissue Plasminogen Activator Administration in Acute Ischemic Stroke,” Stroke, Vol. 30, No. 11, 1999, pp. 2366-2368.
M. B. Conroy, S. U. Rodriguez, S. E. Kimmel and S. E. Kasner, “Helicopter Transfer Offers Benefit to Patients with Acute Stroke,” Stroke, Vol. 30, 1999, pp. 2580-2584. http://dx.doi.org/10.1161/01.STR.30.12.2580
K. R. Lees, E. Bluhmki, R. von Kummer, T. G. Brott, D. Toni, J. C. Grotta, G. W. Albers, M. Kaste, J. R. Marler, S. A. Hamilton, B. C. Tilley, S. M. Davis, G. A. Donnan, W. Hacke, A. N. Ecass, E.r.-P.S. Group, K. Allen, J. Mau, D. Meier, G. del Zoppo, D. A. De Silva, K. S. Butcher, M. W. Parsons, P. A. Barber, C. Levi, C. Bladin and G. Byrnes, “Time to Treatment with Intravenous Alteplase and Outcome in Stroke: An Updated Pooled Analysis of ECASS, ATLANTIS, NINDS, and EPITHET Trials,” Lancet, Vol. 375, No. 9727, 2010, pp. 1695-1703. http://dx.doi.org/10.1016/S0140-6736(10)60491-6
J. Svenson, J. O’Connor and M. Lindsay, “Is Air Transport Faster? A Comparison of Air Versus Ground Transport Times for Interfacility Transfers in a Regional Referral System,” Air Medical Journal, Vol. 25, No. 4, 2006, pp. 170-172. http://dx.doi.org/10.1016/j.amj.2006.04.003
T. J. Crocco, J. C. Grotta, E. C. Jauch, S. E. Kasner, R. U. Kothari, B. R. Larmon, J. L. Saver, M. R. Sayre and S. M. Davis, “EMS Management of Acute Stroke—Prehospital Triage (Resource Document to NAEMSP Position Statement),” Prehospital Emergency Care, Vol. 11, No. 3, 2007, pp. 313-317. http://dx.doi.org/10.1080/10903120701347844
L. H. Schwamm, A. Pancioli, J. E. Acker, L. B. Goldstein, R. D. Zorowitz, T. J. Shephard, P. Moyer, M. Gorman, S. C. Johnston, P. W. Duncan, P. Gorelick, J. Frank, S. K. Stranne, R. Smith, W. Federspiel, K. B. Horton, E. Magnis and R. J. Adams, “Recommendations for Establishment of Stroke Systems of Care: Recommendations from the American Stroke Association’s Task Force on the Development of Stroke Systems,” Stroke, Vol. 36, No. 3, 2005, pp. 690-703.
V. Reiner-Deitemyer, Y. Teuschl, K. Matz, M. Reiter, R. Eckhardt, L. Seyfang, C. Tatschl and M. Brainin, “Helicopter transport of Stroke Patients and Its Influence on Thrombolysis Rates: Data from the Austrian Stroke Unit Registry,” Stroke, Vol. 42, No. 5, 2011, pp. 1295-1300. http://dx.doi.org/10.1161/STROKEAHA.110.604710
S. L. Silliman, B. Quinn, V. Huggett and J. G. Merino, “Use of a Field-to-Stroke Center Helicopter Transport Program to Extend Thrombolytic Therapy to Rural Residents,” Stroke, Vol. 34, No. 3, 2003, pp. 729-733. http://dx.doi.org/10.1161/01.STR.0000056529.29515.B2
R. Lambert, S. Cabardis, J. Valance, E. Borge, J. L. Ducasse and J. J. Arzalier, “ Fibrinolysis and Acute Stroke in Maritime Search and Rescue Medical Evacuation,” Annales Françaises d’Anesthésie et de Réanimation, Vol. 27, No. 3, 2008, pp. 249-251. http://dx.doi.org/10.1016/j.annfar.2007.11.023
Y. Nakagawa, S. Morita, K. Akieda, M. Nagayama, I. Yamamoto, S. Inokuchi, S. Oda and M. Matsumae, “Critical role of the Doctor-Heli System on Cerebral Infarction in the Superacute Stage—Report of an Outstanding Pilot Case,” Tokai Journal of Experimental and Clinical Medicine, Vol. 30, No. 2, 2005, pp. 123-126.
L. Candelise, M. Gattinoni, A. Bersano, G. Micieli, R. Sterzi and A. Morabito, “Stroke-Unit Care for Acute Stroke Patients: An Observational Follow-Up Study,” Lancet, Vol. 369, No. 9558, 2007, pp. 299-305. http://dx.doi.org/10.1016/S0140-6736(07)60152-4
K. C. Albright, C. C. Branas, B. C. Meyer, D. E. Matherne-Meyer, J. A. Zivin, P. D. Lyden and B. G. Carr, “ACCESS: Acute Cerebrovascular Care In Emergency Stroke Systems,” JAMA Neurology, Vol. 67, No. 10, 2010, pp. 1210-1218. http://dx.doi.org/10.1001/archneurol.2010.250
M. D. Olson and A. A. Rabinstein, “Does Helicopter Emergency Medical Service Transfer Offer Benefit to Patients with Stroke?” Stroke, Vol. 43, No. 3, 2012, pp. 878-880. http://dx.doi.org/10.1161/STROKEAHA.111.640987
B. P. Walcott, J. V. Coumans, M. K. Mian, B. V. Nahed and K. T. Kahle, “Interfacility Helicopter Ambulance Transport of Neurosurgical Patients: Observations, Utilization, and Outcomes from a Quaternary Care Hospital,” PLoS ONE, Vol. 6, No. 10, 2011, Article ID: e26216. http://dx.doi.org/10.1371/journal.pone.0026216
R. Silbergleit, P. Scott, M. Lowell and R. Silbergleit, “Cost-Effectiveness of Helicopter Transport of Stroke Patients for Thrombolysis,” Academic Emergency Medicine, Vol. 10, No. 9, 2003, pp. 966-972.
E. C. Leira, A. Ahmed, D. L. Lamb, H. M. Olalde, R. C. Callison, J. C. Torner and H. P. Adams Jr., “Extending Acute Trials to Remote Populations: A Pilot Study During Interhospital Helicopter Transfer,” Stroke, Vol. 40, No. 3, 2009, pp. 895-901. http://dx.doi.org/10.1161/STROKEAHA.108.530204
S. Shewakramani, S. H. Thomas, T. H. Harrison and J. D. Gates, “Air Transport of Patients with Unstable Aortic Aneurysms Directly into Operating Rooms,” Prehospital Emergency Care, Vol. 11, No. 3, 2007, pp. 337-342. http://dx.doi.org/10.1080/10903120701348024
C. H. Pieper, J. Smith, G. F. Kirsten and P. Malan, “The Transport of Neonates to an Intensive Care Unit,” South African Medical Journal, Vol. 84, Suppl. 11, 1994, pp. 801-803.
K. Hon, H. Olsen, B. Totapally and T. Leung, “Air Verus Ground Transportation of Artificially Ventilated Neonates: Comparative Differences in Selected Cardiopulmonary Parameters,” Pediatric Emergency Care, Vol. 22, No. 2, 2006, pp. 107-112. http://dx.doi.org/10.1097/01.pec.0000199557.11605.c6
M. Gausche-Hill, R. J. Lewis, S. J. Stratton, B. E. Haynes, C. S. Gunter, S. M. Goodrich, P. D. Poore, M. D. McCollough, D. P. Henderson, F. D. Pratt and J. S. Seidel, “Effect of out-of-Hospital Pediatric Endotracheal Intubation on Survival and Neurological Outcome: A Controlled Clinical Trial,” JAMA, Vol. 283, No. 6, 2000, pp. 783-790. http://dx.doi.org/10.1001/jama.283.6.783
W. W. Tollefsen, C. A. Brown Ⅲ, K. L. Cox and R. M. Walls, “Two Hundred Sixty Pediatric Emergency Airway Encounters by Air Transport Personnel: A Report of the Air Transport Emergency Airway Management (NEAR VI: ‘A-TEAM’) Project,” Pediatric Emergency Care, Vol. 29, No. 9, 2013, pp. 963-968. http://dx.doi.org/10.1097/PEC.0b013e3182a219ea
T. H. Harrison, S. H. Thomas and S. K. Wedel, “Success rates of Pediatric Intubation by a Non-Physician-Staffed Critical Care Transport Service,” Pediatric Emergency Care, Vol. 20, No. 2, 2004, pp. 101-107. http://dx.doi.org/10.1097/01.pec.0000113879.10140.7f
W. W. Tollefsen, J. Chapman, M. Frakes, M. Gallagher, M. Shear and S. H. Thomas, “Endotracheal Tube Cuff Pressures in Pediatric Patients Intubated before Aeromedical Transport,” Pediatric Emergency Care, Vol. 26, No. 5, 2010, pp. 361-363. http://dx.doi.org/10.1097/PEC.0b013e3181db224d
J. Orf, S. H. Thomas, W. Ahmed, L. Wiebe, P. Chamberlin, S. K. Wedel and C. Houck, “Appropriateness of Endotracheal Tube Size and Insertion Depth in Children Undergoing Air Medical Transport,” Pediatric Emergency Care, Vol. 16, No. 5, 2000, pp. 321-327. http://dx.doi.org/10.1097/00006565-200010000-00004
J. W. van Hook, T. G. Leicht, C. L. van Hook, P. L. Dick, G. D. Hankins and C. J. Harvey, “Aeromedical Transfer of Preterm Labor Patients,” Texas Medicine, Vol. 94, No. 11, 1998, pp. 88-90.
M. Ohara, Y. Shimizu, H. Satoh, T. Kasai, S. Takano, R. Fujiwara, Y. Furusawa, S. Kameda, T. Matsumura, H. Narimatsu, E. Kusumi, Y. Kodama, M. Kami, N. Murashige and M. Suzuki, “Safety and Usefulness of Emer-gency Maternal Transport Using Helicopter,” Journal of Obstetrics and Gynaecology Research, Vol. 34, No. 2, 2008, pp. 189-194.
J. A. Russell, “Management of Sepsis,” The New England Journal of Medicine, Vol. 355, No. 16, 2006, pp. 1699-1713. http://dx.doi.org/10.1056/NEJMra043632
D. Reily, E. Tollok, K. Mallitz, C. W. Hanson III and B. D. Fuchs, “Successful Aeromedical Transport Using Inhaled Prostacyclin for a Patient with life-Threatening Hypoxemia,” Chest, Vol. 125, No. 4, 2004, pp. 1579-1581. http://dx.doi.org/10.1378/chest.125.4.1579
E. Vu, R. Wand and R. Schlamp, “Facilitated Delivery of Antidotes by the British Columbia Air Ambulance Service during Secondary Aeromedical Transport in Poisoned or Toxic Patients,” Prehospital Emergency Care, Vol. 11, 2007, p. 135.
S. Thomas, T. Judge, M. J. Lowell, R. D. MacDonald, J. Madden, K. Pickett, H. A. Werman, M. L. Shear, P. Patel, G. Starr, M. Chesney, R. Domeier, P. Frantz, D. Funk and R. D. Greenberg, “Airway Management Success and Hypoxemia Rates in Air and Ground Critical Care Transport: A Prospective Multicenter Study,” Prehospital Emergency Care, Vol. 14, No. 3, 2010, pp. 283-291. http://dx.doi.org/10.3109/10903127.2010.481758
S. H. Thomas, J. Orf, S. K. Wedel and A. K. Conn, “Hyperventilation in Traumatic Brain Injury Patients: Inconsistency between Consensus Guidelines and Clinical Practice,” Journal of Trauma-Injury Infection & Critical Care, Vol. 52, No. 1, 2002, pp. 47-52. http://dx.doi.org/10.1097/00005373-200201000-00010
S. Thomas, “Hyperventilation in Patients with Traumatic Brain Injury: Lessons for the Acute Care Provider,” Salud Ciencia—Journal of the Sociedad Iberoamericana de Información Científica, Vol. 12, 2004, pp. 22-26.
D. Davis, J. Stern, M. Ochs and D. B. Hoyt, “A Follow-Up Analysis of Factors Associated with Head-Injury Mortality after Paramedic Rapid Sequence Intubation,” Journal of Trauma-Injury Infection & Critical Care, Vol. 59, No. 2, 2005, pp. 486-490. http://dx.doi.org/10.1097/00005373-200508000-00037
D. Davis, J. Dunford, M. Ochs, R. Heister, D. Hoyt, M. Ochs and J. V. Dunford, “Ventilation Patterns Following Paramedic Rapid Sequence Intubation of Patients with Severe Traumatic Brain Injury,” Neurocritical Care, Vol. 2, No. 2, 2005, pp. 165-171. http://dx.doi.org/10.1385/NCC:2:2:165
D. P. Davis, J. V. Dunford, J. C. Poste, M. Ochs, T. Holbrook and D. Fortlage, M. J. Size, F. Kennedy and D. B. Hoyt, “The Impact of Hypoxia and Hyperventilation on Outcome Following Paramedic Rapid Sequence Intubation of Patients with Severe Traumatic Brain Injury,” Journal of Trauma-Injury Infection & Critical Care, Vol. 57, No. 1, 2004, pp. 1-10. http://dx.doi.org/10.1097/01.TA.0000135503.71684.C8
M. Helm, R. Schuster, J. Hauke and L. Lampl, “Tight Control of Prehospital Ventilation by Capnography in Major Trauma Victims,” British Journal of Anesthesia, Vol. 90, No. 3, 2003, pp. 327-332. http://dx.doi.org/10.1093/bja/aeg069
B. J. Zink and R. F. Maio, “Out-of-Hospital Endotracheal Intubation in Traumatic Brain Injury: Outcomes Research Provides us with an Unexpected Outcome,” Annals of Emergency Medicine, Vol. 44, No. 5, 2004, pp. 451-453. http://dx.doi.org/10.1016/j.annemergmed.2004.05.001
G. Berlot, C. La Fata, B. Bacer, B. Biancardi, M. Viviani, U. Lucangelo, P. Gobbato, L. Torelli, E. Carchietti, G. Trillo, M. Daniele and A. Rinaldi, “Influence of Prehospital Treatment on the Outcome of Patients with Severe Blunt Traumatic Brain Injury: A Single-Centre Study,” European Journal of Emergency Medicine, Vol. 16, No. 6, 2009, pp. 312-317. http://dx.doi.org/10.1097/MEJ.0b013e32832d3aa1
M. A. Turturro, “Pain, Priorities, and Prehospital Care,” Prehospital Emergency Care, Vol. 6, No. 4, 2002, pp. 486-488. http://dx.doi.org/10.1080/10903120290938238
C. McEachin, J. McDermott and R. Swor, “Few EMS Patients with Lower-Extremity Fractures Receive Prehospital Analgesia,” Prehospital Emergency Care, Vol. 6, No. 4, 2002, pp. 406-410. http://dx.doi.org/10.1080/10903120290938030
R. Swor, C. M. McEachin, D. Seguin and K. H. Grall, “Prehospital Pain Management in Children Suffering Traumatic Injury,” Prehospital Emergency Care, Vol. 9, No. 1, 2005, pp. 40-43. http://dx.doi.org/10.1080/10903120590891930
S. H. Thomas and S. Shewakramani, “Prehospital Trauma Analgesia,” The Journal of Emergency Medicine, Vol. 35, No. 1, 2008, pp. 47-57. http://dx.doi.org/10.1016/j.jemermed.2007.05.041