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Case Report: Mediastinal Ganglioneuroma Presented as Chronic Diarrhea in a Young Saudi Girl
Pediatric Department, Prince Salman North West Armed Forces Hospital Tabuk, Tabuk, Saudi Arabia
Pediatric Department, Prince Salman North West Armed Forces Hospital Tabuk, Tabuk, Saudi Arabia
Department of Surgery, Prince Salman North West Armed Forces Hospital Tabuk, Tabuk, Saudi Arabia
Laboratory and Pathology Department, Prince Salman North West Armed Forces Hospital Tabuk, Tabuk, Saudi Arabia
- 1 Pediatric Department, Prince Salman North West Armed Forces Hospital Tabuk, Tabuk, Saudi Arabia
- 2 Pediatric Department, Prince Salman North West Armed Forces Hospital Tabuk, Tabuk, Saudi Arabia
- 3 Department of Surgery, Prince Salman North West Armed Forces Hospital Tabuk, Tabuk, Saudi Arabia
- 4 Laboratory and Pathology Department, Prince Salman North West Armed Forces Hospital Tabuk, Tabuk, Saudi Arabia
International Journal of Clinical Medicine·Volume 05 (2014)·Pages 420–424·Published 10 April 2014·DOI10.4236/ijcm.2014.57057
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Abstract
Ganglioneuromas (GN) are rare, benign neurogenic tumors that arise from sympathetic ganglia. They are often asymptomatic. However, in rare cases, they may secrete catecholamines, vasoactive intestinal polypeptides (VIP), or androgenic hormones and manifest with flushing, symptoms of catecholamine excess or chronic diarrhea. We report a young Saudi girl with chronic secretory diarrhea, severe hypokalemia and abdominal distension. After an extensive work up, a well-defined hypodense heterogeneous mediastinal mass was noted in radio imaging. A complete recovery was seen after surgical removal of that mediastinal mass which turned to be a ganglioneuroma.
KeywordsGanglioneuromaMediastinumChronic DiarrheaSecretory Diarrhea
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