The Use of Antiepileptic Drugs in Acute Neuropsychiatric Conditions: Focus on Traumatic Brain Injury, Pain, and Alcohol Withdrawal — Oak Academic Publishing
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The Use of Antiepileptic Drugs in Acute Neuropsychiatric Conditions: Focus on Traumatic Brain Injury, Pain, and Alcohol Withdrawal
Division of Psychiatry and Medicine, Massachusetts General Hospital,Boston, MA, USA
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Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
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Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Massachusetts General Hospital, Boston, MA, USA
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Department of Psychiatry, Lahey Medical Center, Burlington, MA, USA
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Division of Psychiatry and Medicine, Massachusetts General Hospital,Boston, MA, USA
1 Division of Psychiatry and Medicine, Massachusetts General Hospital,Boston, MA, USA
2 Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
3 Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital, Massachusetts General Hospital, Boston, MA, USA
4 Department of Psychiatry, Lahey Medical Center, Burlington, MA, USA
5 Division of Psychiatry and Medicine, Massachusetts General Hospital,Boston, MA, USA
Antiepileptic drugs (AEDs), have demonstrated efficacy treating a number of acute conditions, encompassing a broad range of symptoms and syndromes, in addition to being first-line treatment for epilepsy. Clinically, since their inception, AEDs have been used off-label for acute and chronic medical conditions, both as primary and as adjuvant therapies. In this review, we describe the ob served clinical effectiveness of AEDs across a set of commonly encountered acute conditions in the general hospital: traumatic brain injury, pain, alcohol withdrawal. In describing the individual benefits and usages of specific agents, the applicability of these agents to other common neuropsychiatric conditions may be further explored.
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