Outcomes of Laparoscopic Cholecystectomy in Patients with End-Stage Renal Disease

Abstract

Purpose: In this study, we aimed to discuss the laparoscopic cholecystectomy in patients with end stage renal disease compared to the general population. Materials and Methods: We retrospectively evaluated a group of patients with (n = 45) and without (n = 90) end-stage renal disease undergoing laparoscopic cholecystectomy. The groups were compared in terms of length of surgery; duration of hospitalization after surgery; use of blood derivatives; mortality rates; and perioperative, postoperative, and postdischarge complications. Results: Patients with end-stage renal disease exhibited a higher frequency of associated diseases; lower hemoglobin levels; and elevated alkaline phosphatase, blood urea nitrogen, and creatinine values. Statistically significant differences were found between the two groups regarding length of surgery (83.6 ± 14.88 vs. 71.7 ± 11.42 minutes; p < 0.001); duration of hospitalization (1.7 ± 0.47 vs. 1.4 ± 0.31 days; p < 0.001). In the group of patients with end-stage renal disease had significantly higher perioperative ( p = 0.011), postoperative ( p < 0.001), and postdischarge complication ( p = 0.011) rates. Among all patients with end-stage renal disease, 12 (26.7%) were converted to an open procedure ( p < 0.001). Conclusion: Despite higher complication rates of laparoscopic cholecystectomy in end-stage renal disease patients, laparoscopic cholecystectomy could be performed safely in patients with end-stage renal disease with low levels of complications and no associated mortality.