I have reached the conclusion that the human nose might be involved in cooling of the brain. In this report, I first describe the clinical observations about ankyloglossia with deviation of the epiglottis and larynx (ADEL) with regard to sleep that I have made during my 30 years of otorhino-laryngological experience. Then I describe the physiology of the nose. Next I quote from reports on paradoxical sleep, or REM sleep, from Kitamura K (2009) and Jouvet M (1992). Finally, I present the conclusion that nasal respiration is indispensable to a deep and sound sleep that refreshes humans and promotes vitality.
KeywordsNoseSleepParadoxical SleepREMADELCGLEVO
Paré, A. (1970) De l’empeschementet retraction de la langve. Amboise Paré; Oevres Complétes. J. F. Malgaigne. Genève, Slatkine Reprinte. II: 455-456.
Paré, A. (2010) The Book of Surgery. Uo, G., Ed., Linker, W. and Womack, N., Trans., The University of Georgia Press, Athens, 1575.
Loux, F. (1978) Le jeune enfant et son corps dans la médecine traditionnelle. Flammarion, Paris.
Mukai, S., Mukai, C. and Asaoka, K. (1991) Congenital Ankyloglossia with Deviation of the Epiglottis and Larynx. Annals of Otolaryngology, 100, 1-20.
Mukai, S., Mukai, C. and Asaoka, K. (1993) Congenital Ankyloglossia with Deviation of the Epiglottis and Larynx: Symptoms and Respiratory Function in Adult. Annals of Otology, Rhinology & Laryngology, 102, 620-624. http://dx.doi.org/10.1177/000348949310200810
Mukai, S. and Mukai, C. (1991) New Disease with Ankyloglossia and Dislocation of the Epiglottis and of the Larynx—Dyspnea of the Newborn and Suckling Infants. In: Takishima, H., Ed., Advances in the Biosciences, Pergamon Press, New York, 191-193.
Mukai, S., Mukai, C., Asaoka, K. and Nagasugi, S. (1992) Digit Sucking. Lancet, 339, 1545-1546. http://dx.doi.org/10.1016/0140-6736(92)91316-Z
Mukai, S., Mukai, C., Asaoka, K., Nagasugi, S. and Ogiyam, M. (1991) Postoperative Changes in Infant with ADEL. Zetuyuchalushou Kenkyuukai Kaiho (Annals ADEL), 1, 35-45. (In Japanese with English Abstract)
Mukai, S., Mukai, C. and Asaoka, K. (1990) Congenital Ankyloglossia with Deviation of the Epiglottis and Larynx— Respiratory Insufficiency of the Children. Journal of Clinical Otolaryngology (Kyoto), 83, 1043-1065. (In Japanese with English Abstract)
Mukai, S. (1995) Changes after Correction of the Epiglottis and Larynx (CGL). Zetuyuchakusho Kennkyuukai Kaiho, 5, 82-92. (In Japanese)
Mukai, S. and Nitta, N. (2004) Expansion of the Vestibular Oris (EVO). Nihon Zetuychakusho Gakkai Kaishi (Annals ADEL), 12, 1-9. (In Japanese)
Mukai, S. (2010) Expansion of the Vestibular Oris (EVO)—Esthetic Facial Changes and Expansion of the Nasal Cavity. Nihon Zetuychakusho Gakkai Kaishi (Annals ADEL), 16, 32-41.
Mukai, S. (2013) Dilatation of the Nasal Valve by Expansion of the Vestibular Oris (EVO). Health, 5, 21-25. http://dx.doi.org/10.4236/health.2013.58A2004
Mukai, S., Mukai, C. and Nitta, M. (2000) Function of the Uvula and Z-Pharyngoplasty. Psychiatry and Clinical Neurosciences, 54, 346-347. http://dx.doi.org/10.1046/j.1440-1819.2000.00708.x
Mukai, S., Mukai, C. and Nitta, M. (2000) Function of the Uvula and Z-Pharyngoplasty. Practica Oto-Rhino-Laryngologica, 93, 31-38. (In Japanese with English Abstract) https://www.jstage.jst.go.jp/article/jibirin1925/93/1/93_1_31/_article
Mukai, S., Yamamoto, W., Suzuki, M. and Asaoka, K. (1980) Postoperative Headache in Oto-Rhino-Laryngology: Especially on after Nasal Obstruction. Nihon Jibiinkoka Gakkai Kaiho, 83, 960-965. http://dx.doi.org/10.3950/jibiinkoka.83.960
Mukai, S. (2013) Vicissitude of Curetted Adenoid Vegetations. International Journal of Clinical Medicine, 4, 251-256. http://www.scirp.org/journal/ijcm http://dx.doi.org/10.4236/ijcm.2013.45044
Mukai, S. (2011) Tonsils Increases in Weight during Growth, Moreover There Are Gender Differences. Optimumtime of Tonsilectomy Is between Two to Four. Zetuyuchakushogakkaishi, Annals of the Ankyloglossia with Deviation of the Epiglottis and Larynx, 17, 19-26. (In Japanese)
Cottle, M.H. (1955) The Structure and Function of the Nasal Vestibule. Archives of Otolaryngology—Head & Neck Surgery, 62, 173-181. http://dx.doi.org/10.1001/archotol.1955.03830020055011
Bridger, G.P. (1970) Physiology of the Nasal Valve. Archives of Otolaryngology—Head & Neck Surgery, 92, 543-553. http://dx.doi.org/10.1001/archotol.1970.04310060015005
Heinberg, C.E. and Kern, E.B. (1973) The Cottle Sign: An Aid in the Physical Diagnose of Nasal Airflow Disturbances. 3rd Congress of the International Rhinologic Society, Bordeaux, 89-94.
Mukai, S. (1989) Larynbgeal Movements during Wind Instruments Play. Nihonn Jibiinnkouka Gakkaihou, 92, 260-270. (Japanese with English Abstract) http://dx.doi.org/10.3950/jibiinkoka.92.260
Mukai, S. (1989) Vocal Cord Adduction While Sniffing. Archives of Otolaryngology—Head & Neck Surgery, 115, 1362-1366. http://dx.doi.org/10.1001/archotol.1989.01860350096023
Mukai, S., Mukai, C. and Suzuki, I., Eds. (1989) Dysosmia with Vocal Cord Paralysis during Sniff, Abstract 740. 14th World Congress of Otorhinolaryngology Head and Neck Surgery, Madrid, 10-15 September 1989.
Mukai, S., Mukai, C. and Suzuki, I., Eds. (1989) Vocal Cords Adduct during Sniff (Abstract), Video. 14th World Congress of Otorhinolaryngology Head and Neck Surgery, Madrid, 10-15 September 1989.
Ganong, W. (1993) Sniffing. In: Ganog, W., Ed., Review of Medical Physiology, 16th Edition, Appleton & Lange, Norwalk, 168-169.
Jouvet, M. (1992) Le sommeil et le rêve. Kitahama, K., Trans., Kinokuniya Shoten Ltd., Tokyo. (In Japanese)
Kitahama, K. (2009) Brain and Sleep. Asakura-Shoten Ltd., Tokyo. (In Japanese)
Mukai, S. (1978) Effect of Nasal Packing on the Respiration (Japanese with English abstract). Nihon Jibiinkoka Gakkai Kaiho, 81, 443-447. http://dx.doi.org/10.3950/jibiinkoka.81.443
Mukai, S. (2013) Tonsils Increase in Weight during Growth. International Journal of Clinical Medicine, 4, 222-227. http://www.scirp.org/journal/ijcm http://dx.doi.org/10.4236/ijcm.2013.44039
Enlow, D.H. and Hans, M.G. (1996) Essentials of Facial Growth. WS Saunders Co., Philadelphia, 1-240.
Takahashi, R. (1987) Why the Nose Is Center of the Face. Tsukijishokann Ltd., Tokyo. (In Japanese)
Michaels, L. and Hellquist, H.B. (2001) Histology of the Nose. In: Michaels, L. and Hellquist, H.B., Eds., Ear, Nose and Throat Histopathology, 2nd Edition, Springer-Verlag London Ltd., London, 139-140.