Retiform Sertoli-Leydig Cell Tumor of the Ovary
- 1 Department of Obstetrics and Gynecology, College of Medicine, Dankook University, Cheonan, Korea
- 2 Department of Pathology, College of Medicine, Dankook University, Cheonan, South Korea
- 3 Department of Obstetrics and Gynecology, College of Medicine, Dankook University, Cheonan, Korea
- 4 Department of Obstetrics and Gynecology, College of Medicine, Dankook University, Cheonan, Korea
Abstract
Sertoli-Leydig cell tumor of the ovary is a kind of sex cord-stromal tumor, which occurs between teens and twenties with symptoms including abdominal pain and swelling. The incidence rate is infinitely rare comprising less than 0.5% of all ovarian tumor. The average age of “retiform Sertoli-Leydig cell tumor” is 17 years as compared to 25 years for Sertoli-Leydig cell tumors as a group. We have experienced this rare case of retiform Sertoli-Leydig cell tumor in a 25-year-old foreign patient with the complaint of palpable mass on the right lower quadrant and an irregular menstrual period. The patient underwent right salpingo-oophorectomy and tumor stage was FIGO stage 1A. We report with a brief review of literature.
- Roth, L.M., Anderson, M.C., Govan, A.D.T., Langley, F.A., Gowing, N.F. and Woodcock, A.S. (1981) Sertoli-Leydig Cell Tumors—A Clinicopathologic Study of 34 Cases. Cancer, 48, 187-197. http://dx.doi.org/10.1002/1097-0142(19810701)48:1 3.0.CO;2-1
- Pick, L. (1905) Ueber Neubildungen am Genitale bei Zwittern nebst Beutraegen zur von den Adenomen des Hodens und Elerstocks. Arch Genaekol, 76, 1912.
- Meyer, R. (1931) Pathology of Some Special Ovarian Tumors and Their Relation to Sex Characteristics. American Journal of Obstetrics & Gynecology, 22, 679-713. http://dx.doi.org/10.1016/S0002-9378(31)90960-5
- Kanter, A.E. and Klawans, A.H. (1940) Arrhenoblastoma of the Ovary. American Journal of Cancer, 40, 474-484.
- Piver, S.M. (1983) Ovarian Malignancies. Current Reviews in Obstetrics and Gynecology. Churchill Livingstone, New York, 183.
- Russel, P. and Bannatyne, P. (1989) Androblastomas. In: Russell, P. and Bannatyne, P., Eds., Surgical Pathology of the Ovaries, Churchill Livingstone, Edinburgh, New York, 346-365.
- Tavassoli, F.A. and Devilee, P., Eds. (2003) World Health Organization Classfication of Tumors. Pathology & Genetics of Tumours of the Breast and Female Genital Organs. IARC (International Agency for Research on Cancer) Press, Lyon, 153-158.
- Roth, L.M., Slayton, R.E., Brady, L.W., Blessing, J.A. and Johnson, G. (1985) Retiform Differentiation in Ovarian Sertoli-Leydig Cell Tumors: A Clinicopathologic Study of Six Cases from a Gynecologic Oncology Group Study. Cancer, 55, 1093-1098. http://dx.doi.org/10.1002/1097-0142(19850301)55:5 3.0.CO;2-O
- Young, R.H. and Scully, R.E. (1983) Ovarian Sertoli-Leydig Cell Tumors with Retiform Pattern: A Problem in Histopathologic Diagnosis. A Report of 25 Cases. American Journal of Surgical Pathology, 7, 755-771. http://dx.doi.org/10.1097/00000478-198307080-00005
- Young, R.H. and Scully, R.E. (1985) Ovarian Sertoli-Leydig Cell Tumors. A Clinico-Pathological Analysis of 207 Cases. American Journal of Surgical Pathology, 9, 543-569. http://dx.doi.org/10.1097/00000478-198508000-00001
- Mooney, E.E., Nogales, F.F., Bergeron, C. and Tavassoli, F.A. (2002) Retiform Sertoli-Leydig Cell Tumours: Clinical, Morphological and Immunohistochemical Findings. Histopathology, 41, 110-117. http://dx.doi.org/10.1046/j.1365-2559.2002.01426.x
- Young, R.H. and Scully, R.E. (2002) Sex Cord-Stromal, Steroid Cell and Other Ovarian Tumors. In: Blaustein, A. and Kurman, R.J., Eds., Blaustein’s Pathology of Female Genital Tract, 5th Edition, Springer, New York, 929-939.