Pattern, Precipitants and Short Term Outcome of Heart Failure Patients Managed at Federal Medical Centre Nguru, a Tertiary Health Centre in Yobe State Northeastern Nigeria
- 1 Department of Internal Medicine, Federal Medical Centre Nguru, Nguru, Nigeria
- 2 Department of Medicine, College of Medical Sciences, University of Maiduguri, Maiduguri, Nigeria
- 3 Department of Medicine, College of Medical Sciences, University of Maiduguri, Maiduguri, Nigeria
- 4 Department of Medicine, College of Medical Sciences, University of Maiduguri, Maiduguri, Nigeria
Abstract
Heart Failure (HF) is a syndrome characterized by typical symptoms (e.g. breathlessness, ankle swelling and fatigue) that may be accompanied by signs (e.g. elevated jugular venous pressure, pulmonary crackles and peripheral oedema) caused by a structural and/or functional cardiac abnormality, resulting in a reduced cardiac output and/or elevated intracardiac pressures at rest or during stress. Clinical studies investigating the aetiological patterns of heart failure in Sub-Saharan Africa (SSA) revealed that hypertension, cardiomyopathy and rheumatic heart disease account for more than two-thirds of cardiac disease cases. The objective of this study therefore is to assess the pattern, precipitating factors and short term outcome of heart failure among patients admitted into our hospital. Method: The study was a prospective cross-sectional type conducted among in patients with heart failure in the medical ward of the hospital. Results: A total of three and fifty four (354) subjects were recruited into the study, comprising one hundred and twenty nine males (36.4%) and two hundred and twenty five (63.4%) females. Majority of the patients were admitted in NYHA functional class IV. This however improved to class II at discharge though few were discharged in NYHA class III. Heart failure secondary to progressive hypertensive heart disease was the most common (39.0%) followed by peripartum cardiomyopathy (22.6%) while idiopathic dilated cardiomyopathy (11.0%) and rheumatic heart disease (7.3%) were the third and fourth causes of heart failure respectively. The most common precipitating factor for heart failure in this study was chest infection (44.9%). In conclusion, the study revealed that progressive hypertensive heart disease was the leading cause of heart failure, followed by peripartum cardiomyopathy while idiopathic dilated cardiomyopathy and rheumatic heart disease were ranked third and fourth causes of heart failure respectively. Though myocardial infarction is on the increase, it was found to be the fifth cause of heart failure. The study also identified the following precipitants of heart failure in decreasing order of occurrence: chest infection, non-adherence to prescription, and urinary tract infection.
- Ponikowski, P., Voors, A.A., Anker, S.D., et al. (2016) ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure. The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure of the European Society of Cardiology (ESC) Developed with the Special Contribution of the Heart Failure Association (HFA) of the ESC. European Journal of Heart Failure, 18, 891-975. https://doi.org/10.1002/ejhf.592
- Hunt, S.A., Abraham, W.T., Chin, M.H., et al. and the American college of Cardiology Foundation; American Heart Association. (2009) Focused Update Incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration with the International Society for Heart and Lung Transplantation. Journal of the American College of Cardiology, 53, e1-e9. https://doi.org/10.1016/j.jacc.2008.11.013
- Yancy, C.W., Jessup, M., Bozkurt, B., et al. (2013) 2013 ACCF/AHA Guideline for the Management of Heart Failure: Executive Summary. Circulation, 128, 1810-1852.
- Ponikowski, P., Voors, A.A., Anker, S.D., et al. (2016) Authors/Task Force Members. 2016 ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure of the European Society of Cardiology (ESC) Developed with the Special Contribution of the Heart Failure Association (HFA) of the ESC. European Heart Journal, 37, 2129-2200. https://doi.org/10.1093/eurheartj/ehw128
- Damasceno, A., Cotter, G., Dzudie, A., Sliwa, K. and Mayosi, B.M. (2007) Heart Failure in Sub-Saharan Africa: Time for Action. Journal of the American College of Cardiology, 50, 1688-1693. https://doi.org/10.1016/j.jacc.2007.07.030
- Mayosi, B.M. (2007) Contemporary Trends in the Epidemiology and Management of Cardiomyopathy and Pericarditis in Sub-Saharan Africa. Heart, 93, 1176-1183. https://doi.org/10.1136/hrt.2007.127746
- Damasceno, A., Mayosi, B.M., Sani, M., et al. (2012) The Causes, Treatment, and Outcome of Acute Heart Failure in 1006 Africans from 9 Countries. Archives of Internal Medicine, 172, 1386-1394. https://doi.org/10.1001/archinternmed.2012.3310
- Dokainish, H., Teo, K., Zhu, J., et al. (2017) Global Mortality Variations in Patients with Heart Failure: Results from the International Congestive Heart Failure (INTER-CHF) Prospective Cohort Study. The Lancet Global Health, 5, e665-e6672. https://doi.org/10.1016/S2214-109X(17)30196-1