Research ArticleOpen AccessGoogle Scholar indexed
Chemotaxonomic Study of the Covid-Organics of Madagascar Based on the Chemical Composition of Their Essential Oils
Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
- 1 Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
- 2 Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
- 3 Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
- 4 Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
- 5 Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
- 6 Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
- 7 Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
- 8 Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
- 9 Laboratoire de Chimie Organique et Thérapeutique, Faculté de Médecine, Pharmacie et Odontologie, Université Cheikh Anta Diop, Dakar, Sénégal
International Journal of Organic Chemistry·Volume 13 (2023)·Pages 50–56·Published 12 June 2023·DOI10.4236/ijoc.2023.132005
Copy link · social · email
Abstract
The aim of this study was to investigate the chemical composition of the essential oils of “Covid-Organics” of Madagascar (62% Artemisia annua and two other undisclosed medicinal plants) used as curative and preventive treatments of Covid-19, to identify its constituent species. The essential oils isolated by hydro-distillation from two samples (curative and preventive) were analyzed by GC-FID and GC-MS. These essential oils (curative and preventive) were mainly dominated by camphor (17.9% and 11.9%, respectively), spathulenol (4.8% and 11.8%, respectively), α -acorenol (4.3% and 3.7%, respectively), ( E )- β -caryophyllene (3.4% and 4.2%, respectively), 1,8-cineole (3.1% and 3.6%, respectively), hexadecanoïc acid (3.8% and 3.2%, respectively) and caryophyllene oxide (3.4% and 2.4%, respectively). From the chemical composition, two species were identified, A. annua characterised by camphor and Cinnamomumcamphora (Ravintsara) characterised by 1,8-cineole and sabinene. However, we were unable to identify the third species.
KeywordsCovid-19Covid-Organics<i>Artemisia annua</i>Essential OilsChemotaxonomic
- Kandel, N., Chungong, S., Omaar, A. and Xing, J. (2020) Health Security Capacities in the Context of Covid-19 Outbreak: An Analysis of International Health Regulations Annual Report Data from 182 Countries. The Lancet, 395, 1047-1053. https://doi.org/10.1016/S0140-6736(20)30553-5
- Zumla, A. and Niederman, M.S. (2020) Editorial: The Explosive Epidemic Outbreak of Novel Coronavirus Disease 2019 (Covid-19) and the Persistent Threat of Respiratory Tract Infectious Diseases to Global Health Security. Current Opinion in Pulmonary Medicine, 26, 193-196. https://doi.org/10.1097/MCP.0000000000000676
- World Health Organization (2022) Statement on the Second Meeting of the International Health Regulations (2005) Emergency Committee Regarding the Outbreak of Novel Coronavirus (2019-nCoV) https://www.who.int/news/item/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov)
- Jean, S.S., Lee, P.I. and Hsueh, P.R. (2020) Treatment Options for Covid-19: The Reality and Challenges. Journal of Microbiology, Immunology and Infection, 53, 436-443. https://doi.org/10.1016/j.jmii.2020.03.034
- Boukhatem, M.N. and Setzer, W.N. (2020) Aromatic Herbs, Medicinal Plant-Derived Essential Oils, and Phytochemical Extracts as Potential Therapies for Coronaviruses: Future Perspectives. Plants, 9, Article 800. https://doi.org/10.3390/plants9060800
- Rakotoarivelo, J. (2022) Covid-Organics: La communauté scientifique sort du silence.
- Woerdenbag, H.J., Pras, N., Chan, N.G., Bang, B.T., Bos, R., van Uden, W., Van Y, P., Van Boi, N., Batterman, S. and Lugt, C.B. (1994) Artemisinin, Related Sesquiterpenes, and Essential Oil in Artemisia annua during a Vegetation Period in Vietnam. Plantamedica ,60, 272-275. https://doi.org/10.1055/s-2006-959474
- Juteau, F., Masotti, V., Bessiere, J.M., Dherbomez, M. and Viano, J. (2002) Antibacterial and Antioxidant Activities of Artemisia annua Essential Oil. Fitoterapia, 73, 532-535. https://doi.org/10.1016/S0367-326X(02)00175-2
- Ćavar, S., Maksimović, M., Vidic, D. and Parić, A. (2012) Chemical Composition and Antioxidant and Antimicrobial Activity of Essential Oil of Artemisia annua L. from Bosnia. Industrial Crops and Products, 37, 479-485.
- Garcia, L.C. (2015) A Review of Artemisia annua L.: Its Genetics, Biochemical Characteristics, and Anti-Malarial Efficacy. International Journal of Science and Technology, 5, 38-46.